The stability of this product in solution for extended periods has not been determined. Stock solutions stored in aliquots at -70°C are stable up to 6 months. Stock solutions may also be stored at -20°C, however no time frame has been established.
C1768
Cytarabine
≥90% (HPLC), crystalline, DNA replication inhibitor
Sinónimos:
(β-D-Arabinofuranosyl)cytosine, Ara-C, Arabinocytidine, Arabinosylcytosine, Cytarabine, Cytosine arabinoside
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| Talla/SKU | Disponibilidad | Precio |
|---|---|---|
100 mg | Póngase en contacto con nuestro Servicio de Atención al Cliente para disponibilidad | 54,40 € |
500 mg | Póngase en contacto con nuestro Servicio de Atención al Cliente para disponibilidad | 134,00 € |
1 g | Póngase en contacto con nuestro Servicio de Atención al Cliente para disponibilidad | 282,00 € |
5 g | Póngase en contacto con nuestro Servicio de Atención al Cliente para disponibilidad | 829,00 € |
Acerca de este artículo
Fórmula empírica (notación de Hill):
C9H13N3O5
Número CAS:
Peso molecular:
243.22
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
EC Number:
205-705-9
MDL number:
Beilstein/REAXYS Number:
89175
Assay:
≥90% (HPLC)
Form:
crystalline
54,40 €
Póngase en contacto con nuestro Servicio de Atención al Cliente para disponibilidad
Servicio técnico
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Permítanos ayudarleNombre del producto
Cytosine β-D-arabinofuranoside, crystalline, ≥90% (HPLC)
Quality Segment
assay
≥90% (HPLC)
form
crystalline
storage temp.
2-8°C
SMILES string
NC1=NC(=O)N(C=C1)[C@@H]2O[C@H](CO)[C@@H](O)[C@@H]2O
InChI
1S/C9H13N3O5/c10-5-1-2-12(9(16)11-5)8-7(15)6(14)4(3-13)17-8/h1-2,4,6-8,13-15H,3H2,(H2,10,11,16)/t4-,6-,7+,8-/m1/s1
InChI key
UHDGCWIWMRVCDJ-CCXZUQQUSA-N
Gene Information
human ... POLA1(5422), POLA2(23649), POLB(5423), POLD1(5424), POLD2(5425), POLD3(10714), POLD4(57804), POLE(5426), POLE2(5427), POLE3(54107), PRIM1(5557), PRIM2(5558)
mouse ... Cda(72269)
Biochem/physiol Actions
Ara-C incorporates into DNA and inhibits DNA replication by forming cleavage complexes with topoisomerase I resulting in DNA fragmentation; does not inhibit RNA synthesis. Anti-leukemia agent.
Features and Benefits
This compound is a featured product for Apoptosis research. Click here to discover more featured Apoptosis products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
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Este artículo | |||
|---|---|---|---|
| description crystalline, ≥90% (HPLC) | description European Pharmacopoeia (EP) Reference Standard | description British Pharmacopoeia (BP) Reference Standard | description United States Pharmacopeia (USP) Reference Standard |
| form crystalline | form - | form crystalline | form - |
| assay ≥90% (HPLC) | assay - | assay - | assay - |
| Quality Level 200 | Quality Level - | Quality Level - | Quality Level - |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C |
| Gene Information human ... POLA1(5422), POLA2(23649), POLB(5423), POLD1(5424), POLD2(5425), POLD3(10714), POLD4(57804), POLE(5426), POLE2(5427), POLE3(54107), PRIM1(5557), PRIM2(5558) | Gene Information human ... POLA1(5422), POLA2(23649), POLD1(5424), POLD2(5425), POLD3(10714), POLD4(57804), POLE(5426), POLE2(5427), POLE3(54107), PRIM1(5557), PRIM2(5558) | Gene Information human ... POLA1(5422), POLA2(23649), POLD1(5424), POLD2(5425), POLD3(10714), POLD4(57804), POLE(5426), POLE2(5427), POLE3(54107), PRIM1(5557), PRIM2(5558) | Gene Information human ... POLA1(5422), POLA2(23649), POLD1(5424), POLD2(5425), POLD3(10714), POLD4(57804), POLE(5426), POLE2(5427), POLE3(54107), PRIM1(5557), PRIM2(5558) |
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EPI (equipos de protección individual)
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
Palabra de advertencia
Danger
Códigos de peligro
Indicaciones de precaución
Hazard Classifications
Muta. 1B - Repr. 2
Clase de almacenamiento
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
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How long could a solution of 2uM be stable at -80C? Would this storage help the aliquots last longer than a year at -20C?
1 respuesta-
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Hello, does the freeze-thaw cycle affect the potency or stability of cytarabine?
1 respuesta-
The freeze-thaw stability of this material in solution has not been determined. However, Cold Spring Harbor Protocols suggests solutions are stable for several weeks when refrigerated. For long term storage, store solutions in working aliquots at −20°C . Please see the link below to review this information:
https://cshprotocols.cshlp.org/content/2008/12/pdb.rec11555.full?text_only=true¿Le ha resultado útil?
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Does cytoine beta d arabinofuranoside (Arac) solution filterable by .22um filter ,, is it good idea to filter ara c
1 respuesta-
This product is soluble in water at 50 mg/mL and may be filter sterilized. It is recommended to use a low protein binding filter membrane, such as PES, to prevent product retention in the filter. Solution stability has not been determined, however, Cold Spring Harbor protocols suggest that the filtered stock solution may be stored refrigerated or frozen.
See the link below to review:
https://cshprotocols.cshlp.org/content/2008/12/pdb.rec11555.full?text_only=true¿Le ha resultado útil?
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