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C0984

Creatine Kinase MB Fraction from human heart

≥70% (SDS-PAGE), liquid

Sinónimos:

CK MB Fraction

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A ustedes/SKUDisponibilidadPrecio
100 μg
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637,00 €

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UNSPSC Code:
12352204
NACRES:
NA.54
MDL number:
Assay:
≥70% (SDS-PAGE)
Biological source:
human heart
Concentration:
≥0.5 mg/mL

637,00 €


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biological source

human heart

Quality Segment

assay

≥70% (SDS-PAGE)

form

liquid

concentration

≥0.5 mg/mL

technique(s)

IR spectroscopy: suitable

suitability

suitable for tissue

UniProt accession no.

application(s)

pharmaceutical

storage temp.

−20°C

Gene Information

human ... CKB(1152), CKM(1158)

General description

Research area: Cell Signaling
Creatine Kinase (CK) comprises M and B subunit and is a dimeric molecule. It is one among the isoenzymes of CK. The enzyme is majorly present in the myocardium.

Application

Creatine Kinase MB Fraction from human heart has been used:
  • as a diagnostic marker for acute myocardial infarction.
  • to identify overlapping absorbance peaks between blood and the cardiac biomarkers.
  • to study the phosphorylation pathway of dioxolane guanosine (DXG) in vivo, a potential treatment of HIV-1 infection.

Biochem/physiol Actions

Creatine Kinase (CK) catalyzes the formation of creatinine from creatine phosphate. The enzyme is associated with coronary performance. Elevated serum levels of CK-MB are prime indicators of myocardial cellular injury. It is regarded as a “gold standard” for myocardial infarction diagnosis. The levels of cardiac troponin I (cTnI) or cardiac troponin T also correlate to higher CK-MB) levels. CK-MB levels may also be elevated in chronic renal failure.

Other Notes

Solution in 5 mM sodium succinate, 10 mM sodium chloride, 1 mM EDTA, 5 mM β-mercaptoethanol, 50% glycerol, pH 7.0.

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Este artículo
C9858C3483M6036
description

≥70% (SDS-PAGE), liquid

description

lyophilized powder

description

≥95% (SDS-PAGE), lyophilized powder

description

≥95% (SDS-PAGE), buffered aqueous glycerol solution

biological source

human heart

biological source

-

biological source

human heart

biological source

human heart

Gene Information

human ... CKB(1152), CKM(1158)

Gene Information

human ... CKM(1158)

Gene Information

human ... CYCS(54205), CYCSL1(157317)

Gene Information

human ... MB(4151)

assay

≥70% (SDS-PAGE)

assay

-

assay

≥95% (SDS-PAGE)

assay

≥95% (SDS-PAGE)

technique(s)

IR spectroscopy: suitable

technique(s)

-

technique(s)

cell culture | mammalian: suitable, mass spectrometry (MS): suitable, western blot (chemiluminescent): suitable

technique(s)

-

concentration

≥0.5 mg/mL

concentration

-

concentration

-

concentration

-

form

liquid

form

lyophilized powder

form

lyophilized powder

form

buffered aqueous glycerol solution


Clase de almacenamiento

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable



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Preguntas

1–2 de 2 Preguntas  
  1. What is the Department of Transportation shipping information for this product?

    1 respuesta
    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

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  2. What does the MB stand for in Product C0984, Creatine Kinase MB Fraction from human heart?

    1 respuesta
    1. Creatine Kinase is a dimer that exists as three isozymes: MM (muscle), MB (hybrid) and BB (brain).

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