C0256

Cytidine 5′-diphosphocholine sodium salt dihydrate

~98%, from yeast, solid

• Sinónimos: CDP-choline-Na, CDP-coline, Citicoline sodium, P′-[2-(Trimethylammonio)­ethyl]­ester cytidine 5′-(tri­hydro­gen di­phos­phate) inner salt monosodium
• Fórmula empírica (notación de Hill): C₁₄H₂₅N₄NaO₁₁P₂ · 2H₂O
• Número CAS: 33818-15-4
• Peso molecular: 546.34
• UNSPSC Code: 41106300
• NACRES: NA.77
• PubChem Substance ID: 24278064
• MDL number: MFCD00150508
• Beilstein/REAXYS Number: 4110040
• Assay: ~98%
• Form: solid

Propiedades

• biological source: yeast
• Quality Segment: 200
• assay: ~98%
• form: solid
• color: white
• solubility: H₂O: 100 mg/mL
• storage temp.: −20°C
• SMILES string: [Na+].C[N+](C)(C)CCOP([O-])(=O)OP([O-])(=O)OCC1OC([C@H](O)[C@@H]1O)N2C=CC(N)=NC2=O
• InChI: 1S/C14H26N4O11P2.Na/c1-18(2,3)6-7-26-30(22,23)29-31(24,25)27-8-9-11(19)12(20)13(28-9)17-5-4-10(15)16-14(17)21;/h4-5,9,11-13,19-20H,6-8H2,1-3H3,(H3-,15,16,21,22,23,24,25);/q;+1/p-1/t9?,11-,12-,13?;/m1./s1
• InChI key: YWAFNFGRBBBSPD-MBWJOHGMSA-M

Descripción

General description

Cytidine 5′-diphosphocholine (CDP-choline) contains cytidine and choline linked via a diphosphate bridge.

Application

Cytidine 5′-diphosphocholine sodium salt dihydrate has been used as a physiological metabolite for the identification of gemcitabine diphosphate choline (GdPC) by liquid chromatography-mass spectrometry (LC-MS/MS) method in the Kennedy pathway .

Biochem/physiol Actions

Cytidine 5′-diphosphocholine (CDP-choline) plays an important role in the synthesis of phosphatidylcholine. It is also involved in the biosynthesis of acetylcholine, a neurotransmitter. CDP-choline has therapeutic effects against hypoxia, cerebral ischemia and traumatic brain injury. It also exhibits therapeutic effects against learning and memory disorders, drug addiction and Alzheimer′s and Parkinson′s diseases.

Disclaimer

Hygroscopic

Información de seguridad

• Clase de almacenamiento: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)