B6936

3-Benzidino-6-(4-chlorophenyl)pyridazine

≥98% (HPLC), solid

• Sinónimos: BCP
• Fórmula empírica (notación de Hill): C₂₂H₁₇N₄Cl
• Número CAS: 901773-91-9
• Peso molecular: 372.85
• NACRES: NA.77
• PubChem Substance ID: 329773289
• UNSPSC Code: 12352202
• MDL number: MFCD11046030
• Assay: ≥98% (HPLC)
• Form: solid

Propiedades

• assay: ≥98% (HPLC)
• form: solid
• color: light yellow
• solubility: DMSO: >14 mg/mL
• storage temp.: 2-8°C
• SMILES string: Nc1ccc(cc1)-c2ccc(Nc3ccc(nn3)-c4ccc(Cl)cc4)cc2
• InChI: 1S/C22H17ClN4/c23-18-7-1-17(2-8-18)21-13-14-22(27-26-21)25-20-11-5-16(6-12-20)15-3-9-19(24)10-4-15/h1-14H,24H2,(H,25,27)
• InChI key: ABGCSSPCKSVMHI-UHFFFAOYSA-N

Descripción

Biochem/physiol Actions

3-Benzidino-6-(4-chlorophenyl)pyridazine is an inhibitor of delayed rectifier and transient outward potassium currents.

3-Benzidino-6-(4-chlorophenyl)pyridazine is an inhibitor of delayed rectifier and transient outward potassium currents. The IC50 values for the blocking action of BCP on IKDR and IKA was calculated as 7.13 μM and 0.55 μM, respectively in acutely isolated rat hippocampal pyramidal neurons by using whole-cell patch-clamp technique. The parent compound, minaprine (Cat. No. M3157), has selective affinity for M1 muscarinic receptors and possesses memory-enhancing properties and also acts as an antidepressant.

Features and Benefits

This compound is featured on the Potassium Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Información de seguridad

• pictograms: GHS06
• signalword: Danger
• hcodes: H301
• pcodes: P264 - P270 - P301 + P310 - P405 - P501
• Hazard Classifications: Acute Tox. 3 Oral
• Clase de almacenamiento: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Faceshields, Gloves