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B6936

Sigma-Aldrich

3-Benzidino-6-(4-chlorophenyl)pyridazine

≥98% (HPLC), solid

Sinónimos:

BCP

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About This Item

Fórmula empírica (notación de Hill):
C22H17N4Cl
Número de CAS:
901773-91-9
Peso molecular:
372.85
Número MDL:
MFCD11046030
Código UNSPSC:
12352202
ID de la sustancia en PubChem:
329773289
NACRES:
NA.77

Análisis

≥98% (HPLC)

formulario

solid

color

light yellow

solubilidad

DMSO: >14 mg/mL

temp. de almacenamiento

2-8°C

cadena SMILES

Nc1ccc(cc1)-c2ccc(Nc3ccc(nn3)-c4ccc(Cl)cc4)cc2

InChI

1S/C22H17ClN4/c23-18-7-1-17(2-8-18)21-13-14-22(27-26-21)25-20-11-5-16(6-12-20)15-3-9-19(24)10-4-15/h1-14H,24H2,(H,25,27)

Clave InChI

ABGCSSPCKSVMHI-UHFFFAOYSA-N

Acciones bioquímicas o fisiológicas

3-Benzidino-6-(4-chlorophenyl)pyridazine is an inhibitor of delayed rectifier and transient outward potassium currents. The IC50 values for the blocking action of BCP on IKDR and IKA was calculated as 7.13 μM and 0.55 μM, respectively in acutely isolated rat hippocampal pyramidal neurons by using whole-cell patch-clamp technique. The parent compound, minaprine (Cat. No. M3157), has selective affinity for M1 muscarinic receptors and possesses memory-enhancing properties and also acts as an antidepressant.

Características y beneficios

This compound is featured on the Potassium Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Pictogramas

Skull and crossbones
GHS06

Palabra de señalización

Danger

Frases de peligro

H301

Clasificaciones de peligro

Acute Tox. 3 Oral

Código de clase de almacenamiento

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Equipo de protección personal

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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