B2629
Betaine
≥98% (perchloric acid titration)
Sinónimos:
(Carboxymethyl)trimethylammonium inner salt, Oxyneurine, Trimethylglycine
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About This Item
Fórmula lineal:
(CH3)3N+CH2COO-
Número de CAS:
Peso molecular:
117.15
Beilstein:
3537113
Número CE:
Número MDL:
Código UNSPSC:
12352202
ID de la sustancia en PubChem:
NACRES:
NA.77
Productos recomendados
origen biológico
sugar beets
Nivel de calidad
Ensayo
≥98% (perchloric acid titration)
Formulario
powder or crystals
mp
310 °C (dec.)
solubilidad
water: 50 mg/mL, clear, colorless to faintly yellow
temp. de almacenamiento
2-8°C
cadena SMILES
C[N+](C)(C)CC([O-])=O
InChI
1S/C5H11NO2/c1-6(2,3)4-5(7)8/h4H2,1-3H3
Clave InChI
KWIUHFFTVRNATP-UHFFFAOYSA-N
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Descripción general
Betaine is a quaternary ammonium zwitterion, extensively present in animals, plants and microorganisms. It also forms a good dietary source as it is found in wheat, spinach, shellfish and sugar beets. Betaine is a methyl derivative of the amino acid glycine. It is known by different names such as trimethylglycine, glycine betaine, lycine and oxyneurine.
Aplicación
Betaine has been used to study the effects of antioxidants on regrowth from cryopreservation.
Acciones bioquímicas o fisiológicas
Apart from betaine taking part in transmethylation, it acts as an organic osmolyte in protecting cells under stress. This is being significantly observed in plants and microorganisms. Betaine is also known to increase the levels of S-adenosylmethionine and thus this might reduce the effects of hepatic steatosis.
End-product of oxidative metabolism of choline, betaine is a general methyl donor, in particular in a minor pathway of methionine biosynthesis. It is used to treat homocystinuria, which is a defect in the major pathway of methionine biosynthesis.
Código de clase de almacenamiento
11 - Combustible Solids
Clase de riesgo para el agua (WGK)
WGK 1
Punto de inflamabilidad (°F)
Not applicable
Punto de inflamabilidad (°C)
Not applicable
Equipo de protección personal
Eyeshields, Gloves, type N95 (US)
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Experimental autoimmune uveitis (EAU) is an animal model of human autoimmune uveitis that is characterized by the infiltration of autoimmune T cells with concurrent increases in pro-inflammatory cytokines and reactive oxygen species. This study aimed to assess whether betaine regulates
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The effective cryopreservation of mesenchymal stem cells (MSCs) is indispensable to the operation of basic research and clinical transplantation. The prevalent protocols for MSC cryopreservation utilize dimethyl sulfoxide (DMSO), which is easily permeable and able to protect MSCs from cryo-injuries
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