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A9646

Sigma-Aldrich

N-Acetylneuraminic acid

from sheep submaxillary glands, ≥99%

Sinónimos:

5-Acetamido-3,5-dideoxy-D-glycero-D-galactononulosonic acid, Lactaminic acid, NAN, NANA, Sialic acid

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About This Item

Fórmula empírica (notación de Hill):
C11H19NO9
Número de CAS:
131-48-6
Peso molecular:
309.27
Beilstein:
1716283
Número CE:
205-023-1
Número MDL:
MFCD00006620
Código UNSPSC:
12352201
ID de la sustancia en PubChem:
24891482
En este momento no podemos mostrarle ni los precios ni la disponibilidad

origen biológico

sheep submaxillary glands

tpo

Type VIII

Ensayo

≥99%

temp. de almacenamiento

−20°C

cadena SMILES

O[C@@]1(O[C@@]([C@@H]([C@H](C1)O)NC(C)=O)([H])[C@@H]([C@@H](CO)O)O)C(O)=O

InChI

1S/C11H19NO9/c1-4(14)12-7-5(15)2-11(20,10(18)19)21-9(7)8(17)6(16)3-13/h5-9,13,15-17,20H,2-3H2,1H3,(H,12,14)(H,18,19)/t5-,6+,7+,8+,9+,11-/m0/s1

Clave InChI

SQVRNKJHWKZAKO-PFQGKNLYSA-N

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Acciones bioquímicas o fisiológicas

Both sialic acid and neuraminic acid are loosely used to refer to conjugates of neuraminic acid. N-Acetylneuraminic acid is often found as the terminal sugar of cell surface glycoproteins. Cell surface glycoproteins have important roles in cell recognition and interaction as well as in cell adhesion. Membrane glycoproteins are also important in tumor growth and metastases.

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Certificados de análisis (COA)

Lot/Batch Number
016K1485
114H0396
042K1647
048H0436
043H0036

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Inessa Schwab et al.
Nature reviews. Immunology, 13(3), 176-189 (2013-02-16)
Intravenous immunoglobulin (IVIG) preparations comprise pooled IgG antibodies from the serum of thousands of donors and were initially used as an IgG replacement therapy in immunocompromised patients. Since the discovery, more than 30 years ago, that IVIG therapy can ameliorate
S Joshi et al.
The Journal of clinical pediatric dentistry, 37(3), 309-313 (2013-07-17)
The aim of present study was to evaluate the salivary sialic acid levels in Acute Lymphoblastic Leukemic (ALL) children and to correlate it with dental caries experience. A total of 120 children aged 4-10 yrs were divided into 4 groups
Richard J Reimer
Molecular aspects of medicine, 34(2-3), 350-359 (2013-03-20)
Molecular studies have determined that the SLC17 transporters, a family of nine proteins initially implicated in phosphate transport, mediate the transport of organic anions. While their role in phosphate transport remains uncertain, it is now clear that the transport of
Nils B Bayer et al.
Molecules (Basel, Switzerland), 18(3), 2571-2586 (2013-02-28)
N-acetylneuraminic acid (Neu5Ac) represents the most common terminal carbohydrate residue in many mammalian glycoconjugates and is directly involved in a number of different physiological as well as pathological cellular processes. Endogenous sialic acids derive from the biosynthetic precursor molecule N-acetyl-D-mannosamine
Xiaoli Xiong et al.
Nature, 499(7459), 496-499 (2013-06-22)
Of the 132 people known to have been infected with H7N9 influenza viruses in China, 37 died, and many were severely ill. Infection seems to have involved contact with infected poultry. We have examined the receptor-binding properties of this H7N9
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