A8381

L-Asparragina monohydrate

≥99% (TLC)

• Sinónimos: 4-Amida del ácido(S)-2-aminosuccínico, 4-Amida del ácido L-aspártico, Ácido (S)-(+)-2-aminosuccinámico
• Fórmula lineal: NH₂COCH₂CH(NH₂)COOH · H₂O
• Número de CAS: 5794-13-8
• Peso molecular: 150.13
• Beilstein: 1723527
• Número CE: 200-735-9
• Número MDL: MFCD00151038
• Código UNSPSC: 12352209
• ID de la sustancia en PubChem: 24891338
• NACRES: NA.26

Propiedades

• Nombre del producto: L-Asparragina monohydrate, ≥99% (TLC)
• origen biológico: synthetic
• Ensayo: ≥99% (TLC)
• Formulario: powder
• color: white to off-white
• mp: 233-235 °C (lit.)
• aplicaciones: cell analysis; peptide synthesis
• cadena SMILES: [H]O[H].N[C@@H](CC(N)=O)C(O)=O
• InChI: 1S/C4H8N2O3.H2O/c5-2(4(8)9)1-3(6)7;/h2H,1,5H2,(H2,6,7)(H,8,9);1H2/t2-;/m0./s1
• Clave InChI: RBMGJIZCEWRQES-DKWTVANSSA-N

Descripción

Descripción general

Asparagine biosynthesis is catalyzed by glutamine-dependent asparagine synthetase in mammalian tissues.[1] Elevated levels of free asparagine is observed in plants facing stress in the form of drought or high salt.[2] It is also present in senescing leaves and germinating seeds.[3]

Aplicación

L-Asparagine monohydrate has been used:

• as a component of Sauton′s and chelated Sauton′s media for mycobacterial growth[4]
• to test its effect in the induction of Ca²⁺ flux in rice roots using aequorin luminescence imaging[5]
• as a component of fermentation medium for the Blakeslea trispora spores[6]

Acciones bioquímicas o fisiológicas

Asparagine has high nitrogen to carbon ratio and is a key regulator for nitrogen storage and transport.[2] Its thermal degradation in the presence of sugars leads to the acrylamide formation in foods.[3] Asparagine serves as an amino acid exchange factor and is essential for amino acid homeostasis. It favors cancer cell proliferation.[7]

L-Asparagine, a proteinogenic amino acid, is used in biomanufacturing cell culture systems for the production of therapeutic recombinant proteins and monoclonal antibodies and in cell culture based research.

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 1
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable
• Equipo de protección personal: Eyeshields, Gloves, type N95 (US)