A8052

Arg-Gly-Asp

≥97% (TLC)

• Sinónimos: L-arginyl-glycyl-L-aspartic acid
• Fórmula empírica (notación de Hill): C₁₂H₂₂N₆O₆
• Número de CAS: 99896-85-2
• Peso molecular: 346.34
• Número MDL: MFCD00057952
• Código UNSPSC: 12352209
• ID de la sustancia en PubChem: 24891310
• NACRES: NA.32

Propiedades

• origen biológico: synthetic
• Análisis: ≥97% (TLC)
• formulario: powder
• técnicas: cell culture | stem cell: suitable
• Nº de acceso UniProt: P02751
• temp. de almacenamiento: −20°C
• cadena SMILES: N[C@@H](CCCNC(N)=N)C(=O)NCC(=O)N[C@@H](CC(O)=O)C(O)=O
• InChI: 1S/C12H22N6O6/c13-6(2-1-3-16-12(14)15)10(22)17-5-8(19)18-7(11(23)24)4-9(20)21/h6-7H,1-5,13H2,(H,17,22)(H,18,19)(H,20,21)(H,23,24)(H4,14,15,16)/t6-,7-/m0/s1
• Clave InChI: IYMAXBFPHPZYIK-BQBZGAKWSA-N
• Información sobre el gen: human ... FN1(2335)

Descripción

Amino Acid Sequence

Arg-Gly-Asp

Descripción general

Arg-Gly-Asp (RGD) is an integrin binding site, which belongs to the class of adhesive proteins. It functions as a brain tumor targeting ligand.

Aplicación

Arg-Gly-Asp has been used:

• to saturate the cell surface Arg-Gly-Asp (RGD) receptors and inhibit marrow stromal cell (MSC) attachment to peptide modified hydrogel
• in adhesion assay
• in inhibition assay to confirm the β1-integrin-dependency of cell adhesion
• in textile fabrication and RGD textile functionalization
• to engineer a population of human dermal fibroblasts with impaired migration
• to modify glass substrate and evaluate the behavior of human bone marrow mesenchymal stem cells (hBM-MSCs)
• in the cell culture of human mammary epithelial cells

Acciones bioquímicas o fisiológicas

Primary sequence involved with the binding of proteins to cell surfaces

Envase

Bottomless glass bottle. Contents are inside inserted fused cone.

Nota de preparación

Tripeptide from the cell-attachment domain of fibronectin

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable
• Equipo de protección personal: Eyeshields, Gloves, type N95 (US)