A7433
Arg-Arg-Leu-Ile-Glu-Asp-Ala-Glu-Tyr-Ala-Ala-Arg-Gly
≥97% (HPLC)
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Fórmula empírica (notación de Hill):
C64H106N22O21
Número CAS:
Peso molecular:
1519.66
UNSPSC Code:
12352200
PubChem Substance ID:
MDL number:
Servicio técnico
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≥97% (HPLC)
storage temp.
−20°C
SMILES string
CC[C@H](C)[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](N)CCCNC(N)=N)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(O)=O
Gene Information
human ... ALK(238), BLK(640)
mouse ... ALK(11682), BLK(12143)
rat ... ALK(266802), BLK(364403)
Biochem/physiol Actions
Substrate for protein tyrosine kinase.
Clase de almacenamiento
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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J Goris et al.
The Biochemical journal, 256(3), 1029-1034 (1988-12-15)
By use of the autophosphorylated epidermal-growth-factor receptor and the synthetic peptide RRLIE-DAEY(P)AARG, representing an autophosphorylation site of the transforming protein of Rous-sarcoma virus, it is demonstrated that the phosphotyrosyl phosphatase activity of the polycation-stimulated phosphatases is substantially increased by an
L J Pike et al.
The Journal of biological chemistry, 261(8), 3782-3789 (1986-03-15)
The insulin receptor/kinase was purified to near homogeneity from human placenta. The purified kinase exhibited a specific activity of 300 nmol/min/mg of protein at 30 degrees C using the synthetic peptide, Arg-Arg-Leu-Ile-Glu-Asp-Ala-Glu-Tyr-Ala-Ala-Arg-Gly, as substrate in the presence of insulin. Treatment
J E Casnellie et al.
Proceedings of the National Academy of Sciences of the United States of America, 79(2), 282-286 (1982-01-01)
The particulate fraction from a lymphoma cell line, LSTRA, was found to contain an apparent high level of tyrosine protein kinase activity. When this fraction was incubated with [gamma-32P]ATP in the presence of 10 mM MnCl2, hydrolyzed, and assayed, 70--80%