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A5843

Sigma-Aldrich

Albúmina from human serum

lyophilized powder, low endotoxin

Sinónimos:

HSA

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About This Item

Número de CAS:
Número CE:
Número MDL:
Código UNSPSC:
12352202
eCl@ss:
42010201
NACRES:
NA.25

origen biológico

human

Análisis

≥96% (agarose gel electrophoresis)

formulario

lyophilized powder

mol peso

monomer calculated mol wt 66478 Da

impurezas

HIV I and HIVII, HCV and HBsAg, tested negative
≤1.0 EU/mg endotoxin

solubilidad

H2O: soluble 50 mg/mL

Nº de acceso UniProt

temp. de almacenamiento

2-8°C

InChI

1S/C3F8/c4-1(5,2(6,7)8)3(9,10)11

Clave InChI

QYSGYZVSCZSLHT-UHFFFAOYSA-N

Información sobre el gen

human ... ALB(213)

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Descripción general

Albumin is the most copious protein in blood plasma. Liver produces human albumin.

Aplicación

Albumin was used to test its effect on the in vitro bactericidal activity of cefditoren against penicillin-resistant Streptococcus pneumonia. It has been clinically used in serious and often life-threatening conditions, such as shock and blood loss due to trauma, burns, and surgery.
Albumin was used to study albumin-induced apoptosis in proximal tubule cells. It was also used in cell adhesion molecules and surface treatment studies.

Acciones bioquímicas o fisiológicas

La seroalbúmina funciona como una proteína transportadora para esteroides, ácidos grasos y hormonas tiroideas, y es vital en la regulación de las presiones osmóticas coloidales de la sangre. También se ha observado que la albúmina se une a sustancias exógenas, en particular medicamentos (ibuprofeno, warfarina) y que influye fuertemente en su farmacocinética. El estrés oxidativo que induce cambios en el estado rédox de la albúmina tiene efectos muy variados sobre su función fisiológica.
Serum albumin functions as a carrier protein for steroids, fatty acids, and thyroid hormones, and is vital in regulating the colloidal osmotic pressures of blood. Albumin is also seen to bind to exogenous substances, particularly drugs (e.g., ibuprofen, warfarin), and strongly influences their pharmacokinetics. Oxidative stress leading to changes in the redox state of albumin has varied effects on its physiological function.

Otras notas

Encontrará más información en seroalbúmina humana.

Cláusula de descargo de responsabilidad

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

Código de clase de almacenamiento

10 - Combustible liquids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Equipo de protección personal

Eyeshields, Gloves


Certificados de análisis (COA)

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