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307M-9

Sigma-Aldrich

Cytokeratin 7 (OV-TL 12/30) Mouse Monoclonal Antibody

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About This Item

Código UNSPSC:
12352203
NACRES:
NA.41

origen biológico

mouse

Nivel de calidad

100
500

conjugado

unconjugated

forma del anticuerpo

diluted ascites fluid

tipo de anticuerpo

primary antibodies

clon

OV-TL 12/30, monoclonal

descripción

For In Vitro Diagnostic Use in Select Regions (See Chart)

formulario

buffered aqueous solution

reactividad de especies

human

envase

vial of 0.1 mL concentrate (307M-94)
vial of 0.5 mL concentrate (307M-95)
bottle of 1.0 mL predilute (307M-97)
vial of 1.0 mL concentrate (307M-96)
bottle of 7.0 mL predilute (307M-98)

fabricante / nombre comercial

Cell Marque

técnicas

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500

isotipo

IgG1κ

control

lung adenocarcinoma

Condiciones de envío

wet ice

temp. de almacenamiento

2-8°C

visualización

cytoplasmic

Información sobre el gen

human ... KRT7(3855)

Descripción general

Anti-cytokeratin 7 reacts with proteins that are found in most ductal, glandular, transitional, and biliary duct epithelial cells. Cytokeratin 7 (CK7) labeling can help distinguish between lung, breast carcinomas, and urothelial carcinomas that are typically stain positive, and colon and prostate carcinomas that typically lack CK7 expression. CK7 is a common marker of primary lung adenocarcinomas and is observed in other primary lung carcinomas and non-pulmonary carcinomas. Anti-cytokeratin 7 has also been useful in the differential diagnosis of ovarianneoplasms.

Calidad


IVD

IVD

IVD

RUO

Ligadura / enlace

Cytokeratin 7 Positive Control Slides, Product No. 307S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Forma física

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Nota de preparación

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Otras notas

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Información legal

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

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Shawn K Murray et al.
The American journal of surgical pathology, 28(9), 1154-1162 (2004-08-19)
We recently identified metastatic prostate carcinoma (PCA) within perirectal lymph nodes (PLNs) from 2 patients undergoing abdominoperineal resection (APR) for rectal adenocarcinoma (RA). As this phenomenon has not been addressed by any studies in the literature and because these positive
W G McCluggage et al.
Histopathology, 47(3), 231-247 (2005-08-24)
The ovary is a common site of metastatic tumour. In many cases of ovarian metastasis there is a known history of malignancy but in other cases the ovarian tumour is the first manifestation of disease. In this review metastatic colorectal
Preetha Ramalingam et al.
Annals of diagnostic pathology, 7(2), 112-119 (2003-04-26)
Carcinomas with micropapillary features have been described in the breast, urinary bladder, lung, and ovary. They are characterized by the presence of micropapillary tufts in clear spaces. Unequivocal vascular invasion is usually present at the periphery of the tumor. Consequently
Kaitlin C Fogg et al.
Cancer letters, 458, 92-101 (2019-05-28)
High-grade serous ovarian cancer (HGSOC) metastasizes when tumor spheroids detach from the primary tumor and re-attach throughout the peritoneal cavity. Once the cancer cells have implanted in these new sites, the development of metastatic lesions is dependent on the disaggregation
V Jerome Marson et al.
Histopathology, 45(2), 125-134 (2004-07-29)
To assess cytokeratin (CK) and thyroid transcription factor (TTF)-1 expression in primary epithelial lung tumours by comparison with non-pulmonary carcinomas and to correlate it with their histological type and grade. Immunohistochemistry using antibodies against CKs 5/6, 7, 19, 20 and

Artículos

Colorectal cancer is the third most common cancer in both men and women. An estimated 136,000 cases of colorectal cancer are expected to occur in 2016.

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