Alginate, a colloidal polyuronic acid structural molecule capable of gelation, is used in the preparation of colloidal biodegradable structures such as gels, biofilms, beads, nanoparticles, and microcapsules suitable for applications that range from gel based separation technologies to drug delivery and cell preservation.
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Artificial cells, blood substitutes, and immobilization biotechnology, 40(1-2), 1-6 (2012-02-01)
Targeted and simultaneous delivery VEGF165b and IFN alpha in anti-angiogenic and other applications could offer several advantages. For this a system was design using artificial cell alginate-poly-L-lysine- alginate (APA) microcapsules. Result confirms the ability of this system for simultaneous production
Osteogenic differentiation of muscle satellite cells induced by platelet-rich plasma encapsulated in three-dimensional alginate scaffold.
Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine, 225(11), 1092-1107 (2012-02-02)
Stem cell cryopreservation in three-dimensional (3D) scaffolds may offer better protection to cells leading to higher survival rates. However, it introduces heterogeneity in cryoprotective agent (CPA) concentrations, durations of exposure to CPA, and freezing and thawing rate within constructs. This
Encapsulation of human islets may prevent their immune rejection when transplanted into diabetic recipients. To assist in understanding why clinical outcomes with encapsulated islets were not ideal, we examined the effect of encapsulation on their global gene (mRNA) and selected
Journal of microencapsulation, 29(5), 445-454 (2012-02-02)
The precipitation technique was used to prepare non-polymeric alendronate nanoparticles. The influence of various formulation parameters on the average particle size was investigated and the effect of various stabilizers (PVA, tween, chitosan, alginate, PEG, HPMC, poloxomers) was evaluated. The selection
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