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15862
Cobalt chloride 0.1 M solution
Sinónimos:
Cobalt(II)-chloride solution, Additive Screening Solution 24/Kit-No 78374
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1 ML
65,10 €
About This Item
Número de CAS:
Número MDL:
Código UNSPSC:
12352302
ID de la sustancia en PubChem:
NACRES:
NA.32
Productos recomendados
Nivel de calidad
densidad
1.01 g/mL at 20 °C
temp. de almacenamiento
2-8°C
cadena SMILES
Cl[Co]Cl
InChI
1S/2ClH.Co/h2*1H;/q;;+2/p-2
Clave InChI
GVPFVAHMJGGAJG-UHFFFAOYSA-L
Aplicación
Acciones bioquímicas o fisiológicas
Cobalt chloride induces hypoxia condition in cells by upregulating hypoxia-inducible factor-1α (HIF-1α), erythropoietin and glycolytic enzymes. It is also responsible for mitochondrial DNA damage in rat neuronal PC12 cells.[3] It is also responsible for the induction of apoptosis.[4]
Cobalt chloride 0.1M solution is an additive screening solution of Additive Screening Kit. Additive Screen kit is designed to allow rapid and convenient evaluation of additives and their ability to influence the crystallization of the sample. The Additive Kit provides a tool for refining crystallization conditions.
Cobalt chloride 0.1M solution is an additive screening solution of Additive Screening Kit. Additive Screen kit is designed to allow rapid and convenient evaluation of additives and their ability to influence the crystallization of the sample. The Additive Kit provides a tool for refining crystallization conditions.
Palabra de señalización
Danger
Frases de peligro
Consejos de prudencia
Clasificaciones de peligro
Aquatic Chronic 2 - Carc. 1B - Repr. 1B
Código de clase de almacenamiento
6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
Clase de riesgo para el agua (WGK)
WGK 3
Punto de inflamabilidad (°F)
Not applicable
Punto de inflamabilidad (°C)
Not applicable
Equipo de protección personal
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
Listados normativos
Los listados normativos se proporcionan para los productos químicos principalmente. Para los productos no químicos sólo se puede proporcionar información limitada. Si no hay ninguna entrada, significa que ninguno de los componentes está en la lista. Es obligación del usuario garantizar el uso seguro y legal del producto.
EU REACH SVHC Candidate List
CAS No.
EU REACH Annex XVII (Restriction List)
CAS No.
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Francesca Lazzara et al.
Frontiers in pharmacology, 11, 1063-1063 (2020-08-28)
Retinal hypoxia is one of the causative factors of diabetic retinopathy and is also one of the triggers of VEGF release. We hypothesized that specific dysregulated miRNAs in diabetic retinopathy could be linked to hypoxia-induced damage in human retinal endothelial
Downregulation of duodenal SLC transporters and activation of proinflammatory signaling constitute the early response to high altitude in humans.
Wojtal KA, et al.
American Journal of Physiology: Gastrointestinal and Liver Physiology, 307, G673-G673 (2014)
Exposure to hypoxia following irradiation increases radioresistance in prostate cancer cells.
Hennessey D, et al.
Urologic Oncology, 31, 1106-1106 (2013)
Mitochondrial DNA damage and a hypoxic response are induced by CoCl(2) in rat neuronal PC12 cells.
Wang G, et al.
Nucleic Acids Research, 28, 2135-2135 (2000)
CoCl(2) induces apoptosis via the 18 kDa translocator protein in U118MG human glioblastoma cells.
Zeno S, et al.
Biochemistry, 48, 4652-4652 (2009)
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