104-05A

Human Epidermal Melanocytes: HEM, adult

• Sinónimos: HEM cells
• Código UNSPSC: 41106514
• NACRES: NA.81

Propiedades

• origen biológico: human skin (normal abdominal)
• Nivel de calidad: 100
• envase: pkg of 500,000 cells
• fabricante / nombre comercial: Cell Applications, Inc
• modo de crecimiento: Adherent
• cariotipo: 2n = 46
• morfología: Epidermal
• técnicas: cell culture | mammalian: suitable
• enfermedades relevantes: metabolic disorders
• Condiciones de envío: dry ice
• temp. de almacenamiento: −196°C

Descripción

Descripción general

Lot specific orders are not able to be placed through the web. Contact your local sales rep for more details.

Epidermal melanocytes are pigment-producing cells located at the basal level of epidermis, where they interact with keratinocytes via cellular processes called dendrites. Melanin, the pigment produced by melanocytes and responsible for skin color, is then transferred to keratinocytes, where it is stored in vesicles called melanosomes located around the nucleus to provide protection from UV radiation. HEM maintain their characteristic shape in culture for many generations. They produce melanin and serve as a useful cell model for the studies of melanocyte proliferation and differentiation, as well as progression of melanocytic neoplasia.

Origen línea celular

Skin

Aplicación

melanin production, melanocyte proliferation, differentiation

Componentes

Basal Medium containing 30% FBS & 10% DMSO

Nota de preparación

• 2nd passage, >500,000 cells in Basal Medium containing 30% FBS & 10% DMSO
• Can be cultured at least 12 doublings

Rutina de subcultivo

Please refer to the HEM Culture Protocol.

Cláusula de descargo de responsabilidad

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable