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Y0000112

Lobeline hydrochloride

European Pharmacopoeia (EP) Reference Standard

Sinónimos:

(−)-Lobeline hydrochloride, α-Lobeline hydrochloride, L-Lobeline hydrochloride

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About This Item

Fórmula empírica (notación de Hill):
C22H27NO2 · HCl
Número de CAS:
134-63-4
Peso molecular:
373.92
Beilstein:
3920196
Número MDL:
MFCD00082455
Código UNSPSC:
41116107
ID de la sustancia en PubChem:
329830851
NACRES:
NA.24

grado

pharmaceutical primary standard

familia API

lobeline

fabricante / nombre comercial

EDQM

mp

183-185 °C (dec.) (lit.)

aplicaciones

pharmaceutical (small molecule)

formato

neat

temp. de almacenamiento

2-8°C

cadena SMILES

Cl[H].CN1[C@@H](CCC[C@@H]1CC(=O)c2ccccc2)C[C@H](O)c3ccccc3

InChI

1S/C22H27NO2.ClH/c1-23-19(15-21(24)17-9-4-2-5-10-17)13-8-14-20(23)16-22(25)18-11-6-3-7-12-18;/h2-7,9-12,19-21,24H,8,13-16H2,1H3;1H/t19-,20+,21-;/m0./s1

Clave InChI

MKMYPTLXLWOUSO-NFQNBQCWSA-N

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Descripción general

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicación

Lobeline hydrochloride EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Envase

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Otras notas

Sales restrictions may apply.

Pictogramas

Skull and crossbones
GHS06

Palabra de señalización

Danger

Frases de peligro

H301 + H331

Clasificaciones de peligro

Acute Tox. 3 Inhalation - Acute Tox. 3 Oral

Código de clase de almacenamiento

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

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Certificados de análisis (COA)

Lot/Batch Number

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Yu-Chieh David Chen et al.
Cell reports, 29(4), 961-973 (2019-10-24)
Taste drives appropriate food preference and intake. In Drosophila, taste neurons are housed in both external and internal organs, but the latter have been relatively underexplored. Here, we report that Poxn mutants with a minimal taste system of pharyngeal neurons
Monzurul Amin Roni et al.
Psychopharmacology, 231(15), 2989-2998 (2014-04-01)
Evidence suggests that neuronal nicotinic acetylcholine receptor (nAChR) ligand lobeline has antidepressant-like properties. The present study investigated the effects of lobeline on nicotine withdrawal-induced depression-like behavior. Adult C57BL/6J mice were exposed to nicotine (200 μg/ml) in drinking solution for 3 weeks. During
Yan Chen et al.
Current biology : CB, 24(17), 1969-1977 (2014-08-19)
Natural foods contain not only nutrients, but also nonnutritious and potentially harmful chemicals. Thus, animals need to evaluate food content in order to make adequate feeding decisions. Here, we investigate the effects of acids on the taste neuron responses and

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