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Merck

T4764

Supelco

Δ9-Tetrahydrocannabinol solution

Δ9-Tetrahydrocannabinol solution

1.0 mg/mL in methanol, analytical standard, for drug analysis

Sinónimos:

Δ1-Tetrahydrocannabinol

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1 ML
176,00 €

176,00 €


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1 ML
176,00 €

About This Item

Fórmula empírica (notación de Hill):
C21H30O2
Número de CAS:
Peso molecular:
314.46
Número CE:
Número MDL:
Código UNSPSC:
41116107
ID de la sustancia en PubChem:
NACRES:
NA.24

176,00 €


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grado

analytical standard, for drug analysis

Nivel de calidad

drug control

Home Office Schedule 2; stupéfiant (France); kontrollierte Droge in Deutschland; (Spain); Decreto Lei 15/93: Tabela IIB (Portugal)

concentración

1.0 mg/mL in methanol

técnicas

HPLC: suitable
gas chromatography (GC): suitable

aplicaciones

pharmaceutical (small molecule)

Formato

single component solution

temp. de almacenamiento

2-8°C

cadena SMILES

[H][C@@]12CCC(C)=C[C@@]1([H])c3c(O)cc(CCCCC)cc3OC2(C)C

InChI

1S/C21H30O2/c1-5-6-7-8-15-12-18(22)20-16-11-14(2)9-10-17(16)21(3,4)23-19(20)13-15/h11-13,16-17,22H,5-10H2,1-4H3/t16-,17-/m1/s1

Clave InChI

CYQFCXCEBYINGO-IAGOWNOFSA-N

Información sobre el gen

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Descripción general

Δ9-Tetrahydrocannabinol, known as THC, is a C21 terpenophenolic compound and is the primary psychoactive cannabinoid present in cannabis and hemp.

Aplicación

The Δ9-Tetrahydrocannabinol analytical standard can be used as follows:
  • Development and validation of a high-performance liquid chromatographic method coupled with UV detection to measure cannabidiol and ∆9-tetrahydrocannabinol in rat plasma samples following their extraction by protein precipitation and liquid-liquid extraction (LLE)
  • Estimation of cannabidiol and ∆9-tetrahydrocannabinol extracted from human plasma samples by liquid-liquid extraction using ultra-performance liquid chromatography with triple quadrupole mass spectrometry
  • Multi-residue analysis of Δ9-tetrahydrocannabinol (THC) and its two degradation products, 11-hydroxy-Δ9-tetrahydrocannabinol and 11-nor-9-carboxy-Δ9-tetrahydrocannabinol, in whole blood samples by QuEChERS extraction and gas chromatography (GC) coupled with tandem mass spectrometry (MS/MS)
  • Optimization of an ultra-high performance supercritical fluid chromatographic (UHPSFC) method, combined with a tandem mass spectrometer (MS/MS) to determine ∆9-tetrahydrocannabinol, along with three of its major metabolites and four synthetic metabolites in wastewater samples following liquid-liquid extraction
  • Development and validation of an ultra high-performance liquid chromatographic (UHPLC) method coupled to photodiode array and mass spectrometry detectors to determine 11 cannabinoids in various Cannabis Sativa samples

Otras notas

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Palabra de señalización

Danger

Clasificaciones de peligro

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Órganos de actuación

Eyes,Central nervous system

Código de clase de almacenamiento

3 - Flammable liquids

Clase de riesgo para el agua (WGK)

WGK 2

Punto de inflamabilidad (°F)

49.5 °F - closed cup

Punto de inflamabilidad (°C)

9.7 °C - closed cup

Equipo de protección personal

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


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Certificados de análisis (COA)

Lot/Batch Number

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Visite la Librería de documentos

M Waldman et al.
Biochemical pharmacology, 85(11), 1626-1633 (2013-03-30)
Tetrahydrocannabinol (THC), the major psychoactive component of marijuana, is a cannabinoid agonist that exerts its effects by activating at least two specific receptors (CB1 and CB2) that belong to the seven transmembrane G-protein coupled receptor (GPCR) family. Both CB1 and
Suspected dronabinol withdrawal in an elderly cannabis-naive medically ill patient.
Russ S Muramatsu et al.
The American journal of psychiatry, 170(7), 804-804 (2013-07-04)
David R Maguire et al.
The Journal of pharmacology and experimental therapeutics, 345(3), 354-362 (2013-03-29)
Cannabinoid receptor agonists enhance the antinociceptive effects of μ-opioid receptor agonists, which suggests that combinations of these drugs might enhance therapeutic effectiveness (e.g., analgesia). However, it is not clear whether combinations of these drugs also enhance abuse or dependence liability.
Li-Jie Cheng et al.
Organic letters, 15(4), 764-767 (2013-01-26)
The highly efficient asymmetric total syntheses of (-)-Δ(8)-tetrahydrocannabinol ((-)-Δ(8)-THC) (13 steps, 35%) and (-)-Δ(9)-tetrahydrocannabinol ((-)-Δ(9)-THC) (14 steps, 30%) have been developed by using ruthenium-catalyzed asymmetric hydrogenation of racemic α-aryl cyclic ketones via dynamic kinetic resolution and intramolecular S(N)Ar cyclization.
Stefan W Toennes et al.
Journal of analytical toxicology, 37(3), 152-158 (2013-02-23)
Oral fluid (OF) tests aid in identifying drivers under the influence of drugs. In this study, 17 heavy cannabis users consumed alcohol to achieve steady blood alcohol concentrations of 0 to 0.7 g/L and smoked cannabis 3 h afterward. OF

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