PHR1638

Alfuzosin hydrochloride

Pharmaceutical Secondary Standard; Certified Reference Material

• Sinónimos: N-(3-((4-Amino-6,7-dimethoxy-2-quinazolinyl)methylamino)propyl)tetrahydro-2-furancarboxamide hydrochloride, Uroxatral hydrochloride
• Fórmula empírica (notación de Hill): C₁₉H₂₇N₅O₄ · HCl
• Número de CAS: 81403-68-1
• Peso molecular: 425.91
• Número MDL: MFCD00879135
• Código UNSPSC: 41116107
• ID de la sustancia en PubChem: 329823527
• NACRES: NA.24

Propiedades

• grado: certified reference material; pharmaceutical secondary standard
• Nivel de calidad: 300
• Agency: traceable to Ph. Eur. A0325800; traceable to USP 1012917
• familia API: alfuzosin
• CofA: current certificate can be downloaded
• envase: ampule of 1 × 1 g
• técnicas: HPLC: suitable; gas chromatography (GC): suitable
• aplicaciones: pharmaceutical (small molecule)
• formato: neat
• temp. de almacenamiento: 2-30°C
• cadena SMILES: Cl.COc1cc2nc(nc(N)c2cc1OC)N(C)CCCNC(=O)C3CCCO3
• InChI: 1S/C19H27N5O4.ClH/c1-24(8-5-7-21-18(25)14-6-4-9-28-14)19-22-13-11-16(27-3)15(26-2)10-12(13)17(20)23-19;/h10-11,14H,4-9H2,1-3H3,(H,21,25)(H2,20,22,23);1H
• Clave InChI: YTNKWDJILNVLGX-UHFFFAOYSA-N
• Información sobre el gen: human ... ADRA1A(148) , ADRA1B(147) , ADRA1D(146)

Descripción

Descripción general

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Aplicación

Alfuzosin hydrochloride may be used as a pharmaceutical reference standard for the quantification of alfuzosin hydrochloride levels in pharmaceutical formulations by reverse phase high-performance liquid chromatography (RP-HPLC), high performance thin layer chromatography (HPTLC) and spectrophotometry.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Acciones bioquímicas o fisiológicas

Alfuzosin hydrochloride is an alpha-adrenergic blocker used to treat benign prostatic hyperplasia (BPH). It works by relaxing the muscles in the prostate and bladder neck, making it easier to urinate.

Nota al pie de página

To see an example of a Certificate of Analysis for this material enter LRAA5304 in the slot below. This is an example certificate only and may not be the lot that you receive.

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable