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Merck

PHR1580

Supelco

Dodecanoic acid

Pharmaceutical Secondary Standard; Certified Reference Material

Sinónimos:

Dodecanoic acid, Lauric acid, NSC 5026

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About This Item

Fórmula lineal:
CH3(CH2)10COOH
Número de CAS:
Peso molecular:
200.32
Beilstein:
1099477
Número CE:
Número MDL:
Código UNSPSC:
41116107
ID de la sustancia en PubChem:
NACRES:
NA.24

grado

certified reference material
pharmaceutical secondary standard

Nivel de calidad

Agency

traceable to Ph. Eur. Y0001474
traceable to USP 1356949

familia API

lauric acid

CofA

current certificate can be downloaded

envase

pkg of 1 g

técnicas

HPLC: suitable
gas chromatography (GC): suitable

aplicaciones

pharmaceutical (small molecule)

formato

neat

temp. de almacenamiento

2-30°C

cadena SMILES

CCCCCCCCCCCC(O)=O

InChI

1S/C12H24O2/c1-2-3-4-5-6-7-8-9-10-11-12(13)14/h2-11H2,1H3,(H,13,14)

Clave InChI

POULHZVOKOAJMA-UHFFFAOYSA-N

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Descripción general

Lauric acid finds wide applications in cosmetics and food products. It has been tested for its use as an enhancer for topical penetration and transdermal absorption. It is used as a stabilizer for oil-in-emulsions.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Aplicación

Lauric acid may be used as a pharmaceutical reference standard for the determination of the analyte in biopharmaceutical formulations by chromatography techniques.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Acciones bioquímicas o fisiológicas

Substrato para CYP 4A11.

Nota de análisis

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Otras notas

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Nota al pie de página

To see an example of a Certificate of Analysis for this material enter LRAC0576 in the slot below. This is an example certificate only and may not be the lot that you receive.

Productos recomendados

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Producto relacionado

Referencia del producto
Descripción
Precios

Pictogramas

Corrosion

Palabra de señalización

Danger

Frases de peligro

Consejos de prudencia

Clasificaciones de peligro

Eye Dam. 1

Código de clase de almacenamiento

13 - Non Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 1

Punto de inflamabilidad (°F)

348.8 °F - closed cup

Punto de inflamabilidad (°C)

176 °C - closed cup


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Certificados de análisis (COA)

Lot/Batch Number

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Visite la Librería de documentos

Handbook of Pharmaceutical Excipients, 28(5), 1194-1210 (2009)
Polysorbate 20 degradation in biopharmaceutical formulations: quantification of free fatty acids, characterization of particulates, and insights into the degradation mechanism
Tomlinson A, et al.
Molecular Pharmaceutics, 12(11), 3805-3815 (2015)
The degradation of polysorbates 20 and 80 and its potential impact on the stability of biotherapeutics
Kishore RSK, et al.
Pharmaceutical Research, 28(5), 1194-1210 (2011)
Pharmaceutical formulation of HSA hybrid coated iron oxide nanoparticles for magnetic drug targeting
Zaloga J, et al.
European Journal of Pharmaceutics and Biopharmaceutics, 101(11), 152-162 (2016)
S E Sivinski et al.
Journal of animal science and biotechnology, 11, 89-89 (2020-09-05)
While feed components capable of modulating the immune system are highly sought after and marketed, often little evidence is available to support functional immune response claims. Thus, a high-throughput in vitro cell screening system was developed to test these compounds

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