PHR1258

Chloroquine phosphate

Pharmaceutical Secondary Standard; Certified Reference Material

• Sinónimos: Chloroquine diphosphate salt, N⁴-(7-Chloro-4-quinolinyl)-N¹,N¹-dimethyl-1,4-pentanediamine diphosphate salt
• Fórmula empírica (notación de Hill): C₁₈H₂₆ClN₃ · 2H₃PO₄
• Número de CAS: 50-63-5
• Peso molecular: 515.86
• Beilstein: 4223142
• Número CE: 200-055-2
• Número MDL: MFCD00069852
• Código UNSPSC: 41116107
• ID de la sustancia en PubChem: 329823259
• NACRES: NA.24

Propiedades

• origen biológico: synthetic
• Nivel de calidad: 300
• grado: certified reference material; pharmaceutical secondary standard
• Agency: BP; EP; USP; traceable to USP 1118000
• presión de vapor: <0.0000001 kPa ( 25 °C)
• familia API: chloroquine
• CofA: current certificate can be downloaded
• envase: pkg of 1 g
• condiciones de almacenamiento: protect from light
• técnicas: HPLC: suitable; gas chromatography (GC): suitable
• color: white to yellow
• pH: 3.5-4.5 (10% in aqueous solution, pH <6.0)
• mp: 200 °C (dec.) (lit.)
• solubilidad: water: 50 g/L; benzene: practically insoluble; chloroform: practically insoluble; ethanol: practically insoluble; ether: practically insoluble
• aplicaciones: pharmaceutical (small molecule)
• Formato: neat
• temp. de almacenamiento: 2-8°C
• cadena SMILES: OP(O)(O)=O.OP(O)(O)=O.CCN(CC)CCCC(C)Nc1ccnc2cc(Cl)ccc12
• InChI: 1S/C18H26ClN3.2H3O4P/c1-4-22(5-2)12-6-7-14(3)21-17-10-11-20-18-13-15(19)8-9-16(17)18;2*1-5(2,3)4/h8-11,13-14H,4-7,12H2,1-3H3,(H,20,21);2*(H3,1,2,3,4)
• Clave InChI: QKICWELGRMTQCR-UHFFFAOYSA-N

Descripción

Descripción general

Chloroquine phosphate is a phosphate salt of chloroquine. It belongs to the class of aminoquinoline drugs utilized as antimalarials and amebicides.[1]

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Aplicación

Chloroquine phosphate may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by thin-layer chromatography (TLC) and liquid chromatography (LC).[2][3]

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Nota de análisis

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Otras notas

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Nota al pie de página

To see an example of a Certificate of Analysis for this material enter LRAB3715 in the slot below. This is an example certificate only and may not be the lot that you receive.

Productos recomendados

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Información de seguridad

• Pictogramas: GHS07
• Palabra de señalización: Warning
• Frases de peligro: H302
• Clasificaciones de peligro: Acute Tox. 4 Oral
• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable