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M9017

Supelco

Mepirizole

analytical standard

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About This Item

Fórmula empírica (notación de Hill):
C11H14N4O2
Número de CAS:
18694-40-1
Peso molecular:
234.25
Número CE:
242-507-1
Número MDL:
MFCD00057351
Código UNSPSC:
41116107
ID de la sustancia en PubChem:
329818077
NACRES:
NA.24

grado

analytical standard

Nivel de calidad

200

técnicas

HPLC: suitable
gas chromatography (GC): suitable

aplicaciones

forensics and toxicology
pharmaceutical (small molecule)
veterinary

formato

neat

temp. de almacenamiento

2-8°C

cadena SMILES

CC1=NC(N2C(OC)=CC(C)=N2)=NC(OC)=C1

InChI

1S/C11H14N4O2/c1-7-5-9(16-3)13-11(12-7)15-10(17-4)6-8(2)14-15/h5-6H,1-4H3

Clave InChI

RHAXSHUQNIEUEY-UHFFFAOYSA-N

Categorías relacionadas

Descripción general

Mepirizole belongs to the class of non-steroidal anti-inflammatory drugs (NSAIDs), widely used in the treatment of pain and inflammation.

Aplicación

Mepirizole may be used as an analytical reference standard for the quantification of the analyte in animal samples using ultra-high-performance liquid chromatography with tandem mass spectrometry.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Pictogramas

Exclamation mark
GHS07

Palabra de señalización

Warning

Clasificaciones de peligro

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Órganos de actuación

Respiratory system

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Equipo de protección personal

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

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Certificados de análisis (COA)

Lot/Batch Number
066H0190
012H0713

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K Takeuchi et al.
Journal of clinical gastroenterology, 21 Suppl 1, S66-S72 (1995-01-01)
We investigated the HCO3- stimulatory mechanism of the nitric oxide (NO) synthase inhibitor NG-nitro-L-arginine methyl ester (L-NAME) in the anesthetized rat duodenum and examined whether L-NAME protects against mepirizole-induced duodenal damage. The proximal duodenal loop was perfused with saline and
Simultaneous determination of thirty non-steroidal anti-inflammatory drug residues in swine muscle by ultra-high-performance liquid chromatography with tandem mass spectrometry
Hu T, et al.
Journal of Chromatography A, 1219, 104-113 (2012)
A Nishida et al.
The Journal of pharmacology and experimental therapeutics, 270(3), 1256-1261 (1994-09-01)
We evaluated the effect of YM022 [(R)-1-[2,3-dihydro-1-(2'- methylphenacyl)-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl]-3- (3-methylphenyl)urea], a potent and selective gastrin/cholecystokinin-B receptor antagonist, on gastric acid secretion and gastric and duodenal lesions in rats. Oral YM022 (0.1-10 mumol/kg), famotidine (0.3-30 mumol/kg) and omeprazole (3-100 mumol/kg) dose-dependently suppressed
S K Sohn et al.
Archives of pharmacal research, 21(3), 241-247 (1999-01-06)
This study was designed to determine biochemical and pharmacological properties of a newly synthesized benzimidazole derivative, 2-amino-4,5-dihydropyrido [1,2-a] thiazolo [5,4-g] benzimidazole (YJA20379-5) in vitro and in vivo. In the leaky membrane vesicles of pig gastric mucosa, YJA20379-5 inhibited the K(+)-stimulated
Junko Tanaka et al.
Arzneimittel-Forschung, 54(4), 221-229 (2004-05-19)
The effects of a new benzimidazole derivative, ME3407 (n-butyl-2-(thiazolo-[5,4-b]pyrid-2-yl) sulfinylacetate, CAS 133903-90-9), on gastric acid secretion and gastric and duodenal ulcers in rats were examined. ME3407, given orally, inhibited dose-dependently (0.3-30 mg/kg) the incidence of gastric lesions such as Shay
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