Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
D3525
Diosmin
analytical standard
Sinónimos:
3′,5,7-Trihydroxy-4′-methoxyflavone 7-rutinoside, Barosmin, Buchu resin, Diosmetin 7-O-rhamnosylglucoside, Diosmetin 7-rutinoside
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About This Item
Fórmula empírica (notación de Hill):
C28H32O15
Número de CAS:
Peso molecular:
608.54
Número CE:
Número MDL:
Código UNSPSC:
41116107
ID de la sustancia en PubChem:
NACRES:
NA.24
Para consultas sobre este producto D3525, póngase en contacto con su oficina o distribuidor locales de Merck. Póngase en contacto con el Servicio técnico
Productos recomendados
grado
analytical standard
Nivel de calidad
técnicas
HPLC: suitable
gas chromatography (GC): suitable
aplicaciones
cleaning products
cosmetics
food and beverages
personal care
Formato
neat
temp. de almacenamiento
2-8°C
cadena SMILES
COc1ccc(cc1O)C2=CC(=O)c3c(O)cc(O[C@@H]4O[C@H](CO[C@@H]5O[C@@H](C)[C@H](O)[C@@H](O)[C@H]5O)[C@@H](O)[C@H](O)[C@H]4O)cc3O2
InChI
1S/C28H32O15/c1-10-21(32)23(34)25(36)27(40-10)39-9-19-22(33)24(35)26(37)28(43-19)41-12-6-14(30)20-15(31)8-17(42-18(20)7-12)11-3-4-16(38-2)13(29)5-11/h3-8,10,19,21-30,32-37H,9H2,1-2H3/t10-,19+,21-,22+,23+,24-,25+,26+,27+,28+/m0/s1
Clave InChI
GZSOSUNBTXMUFQ-YFAPSIMESA-N
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Aplicación
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Acciones bioquímicas o fisiológicas
Citrus flavonoid. Modification of hesperidin. Studied for its chemopreventive properties, including anti-proliferative and anti-inflammatory.
Código de clase de almacenamiento
11 - Combustible Solids
Clase de riesgo para el agua (WGK)
WGK 3
Punto de inflamabilidad (°F)
Not applicable
Punto de inflamabilidad (°C)
Not applicable
Equipo de protección personal
Eyeshields, Gloves, type N95 (US)
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The present investigation was designed to evaluate the efficacy of diosmin against ethanol-induced hepatotoxicity in rats by modulating various mechanisms including ethanol metabolizing enzymes, generation of free radicals, imbalance in oxidant-antioxidant status, oxidative damage to membrane lipids, activation of transcription
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Oxidative stress has been suggested as a contributory factor in development and complication of diabetes. The aim of the study was to evaluate the effect of diosmin (DS) in oxidative stress in streptozotocin-nicotinamide (STZ-NA)-induced diabetic rats by measuring the lipid
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Doxycycline and micronized purified flavonoid fraction (MPFF) modulate vein wall remodeling that may be associated with hypoxia in varicose veins (VVs), vein graft stenosis, and deep venous thrombosis. We recently reported that in vitro exposure of non-VV (NVVs) and VVs
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The present study was aimed to evaluate the antihypertensive effect of diosmin in deoxycorticosterone acetate (DOCA)-salt induced hypertension in male Wistar rats. Hypertension was induced in uninephrectomized rats by weekly twice subcutaneous injection of DOCA (25 mg/kg body weight) and
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What is the Department of Transportation shipping information for this product?
1 respuesta-
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How should Product D3525, Diosmin, be dissolved?
1 respuesta-
Diosmin is soluble in DMSO at 10 mM, per following paper:Zhang, S., et al., "Flavonoids as Aryl Hydrocarbon Receptor Agonists/Antagonists: Effects of Structure and Cell Context." Environ. Health. Perspect., 111, 1877-1882 (2003).
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Does Product D3525, diosmin absorb in the UV spectrum? If so, what is the ?max?
1 respuesta-
Yes. Diosmin has the following UV absorbance properties: λmax: 255 nm, 268 nm, 345 nm (ethanol) Extinction coefficient: EmM = 19.05, 17.78, and 19.95.Referenced from: chemicals encyclopedia published by the Royal Society of Chemistry, 10th ed., Entry# 3300.
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Is Product D3525, Diosmin, synthetic or from a natural source?
1 respuesta-
Diosmin is typically isolated from a plant source (orange or lemon). This information can be found on Certificate of Origin (CofO lot-specific). The link to CofO is located on the Product Detail Page.
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Product D3525, Diosmin, is a rutinoside derivative. Does Sigma-Aldrich list any other rutinosides?
1 respuesta-
Yes, we have two others: H5254, Hesperidin and 36428, Keracynin chloride.
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