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90568

Supelco

Fenofibric acid

analytical standard

Sinónimos:

2-[4-(4-Chlorobenzoyl)phenoxy]-2-methylpropionic acid, Fenofibric acid

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About This Item

Fórmula empírica (notación de Hill):
C17H15ClO4
Número de CAS:
42017-89-0
Peso molecular:
318.75
Beilstein:
2058973
Número CE:
255-626-9
Número MDL:
MFCD00792461
Código UNSPSC:
77101502
ID de la sustancia en PubChem:
329769927
NACRES:
NA.24

grado

analytical standard

Nivel de calidad

100

Análisis

≥98.0% (HPLC)

caducidad

limited shelf life, expiry date on the label

técnicas

HPLC: suitable
gas chromatography (GC): suitable

impurezas

≤1.0% water

aplicaciones

forensics and toxicology
pharmaceutical (small molecule)

formato

neat

cadena SMILES

O=C(C1=CC=C(OC(C)(C)C(O)=O)C=C1)C2=CC=C(Cl)C=C2

InChI

1S/C17H15ClO4/c1-17(2,16(20)21)22-14-9-5-12(6-10-14)15(19)11-3-7-13(18)8-4-11/h3-10H,1-2H3,(H,20,21)

Clave InChI

MQOBSOSZFYZQOK-UHFFFAOYSA-N

Información sobre el gen

human ... PPARA(5465)

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Aplicación

Fenofibric acid may be used as a reference standard in the determination of fenofibric acid in samples of human plasma using high performance liquid chromatography (HPLC) and liquid chromatography coupled with tandem mass spectrometry (LC-MS-MS).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Pictogramas

Exclamation markEnvironment
GHS07,GHS09

Palabra de señalización

Warning

Frases de peligro

H302 - H410

Clasificaciones de peligro

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

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Certificados de análisis (COA)

Lot/Batch Number
BCCH7546
BCCG5448
BCCC0735
BCBZ6721
BCBW7364

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Determination of bezafibrate, ciprofibrate and fenofibric acid in human plasma by high-performance liquid chromatography.
Masnatta D L, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 687(2), 437-442 (1996)
Simultaneous determination of rosuvastatin and fenofibric acid in human plasma by LC?MS/MS with electrospray ionization: assay development, validation and application to a clinical study.
Trivedi K R, et al.
Journal of Pharmaceutical and Biomedical Analysis, 39(3-4), 661-669 (2005)
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Paclitaxel-induced peripheral neuropathy (PIPN) is a major adverse effect of this chemotherapeutic agent that is used in the treatment of a number of solid malignancies. PIPN leads notably to burning pain, cold and mechanical allodynia. PIPN is thought to be
Roger K Verbeeck et al.
Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques, 18(1), 61-67 (2015-04-17)
The therapeutic equivalence of multiple registered fenofibrate formulations, several of which are suprabioavailable and therefore marketed at lower dosage strengths than their reference products, is based on the results of bioequivalence studies. Most of these formulations show a higher bioavailability
Yunxia Lu et al.
Biochemical and biophysical research communications, 458(1), 1-7 (2015-01-17)
Fenofibrate (FF) is widely used to lower blood lipids in clinical practice, but whether its protective effect on endothelium-dependent vasodilatation (EDV) in thoracic aorta is related with endoplasmic reticulum (ER) stress remains unknown. In this study, female Sprauge Dawley rats
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