Journal of ethnopharmacology, 103(3), 484-490 (2005-10-11)
The hepatoprotective effects of rubiadin, a major constituent isolated from Rubia cordifolia Linn., were evaluated against carbon tetrachloride (CCl4)-induced hepatic damage in rats. Rubiadin at a dose of 50, 100 and 200 mg/kg was administered orally once daily for 14
The isolation, characterisation and quantification of anthraquinones, from hypogeal apparatus of Rubia peregrina L. (Wild Madder) growing wild in Sardinia (Italy) are described. The present study allowed us to perform an easy and fast HPLC analytical method for the detection
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 47(4), 752-759 (2009-01-27)
Madder color (MC) has been shown to exert carcinogenic potential in the rat kidney in association with degeneration, karyomegaly, increased cell proliferation of renal tubule cells and increased renal 8-OHdG levels. To clarify the causal relationship of components and metabolites
Indian journal of biochemistry & biophysics, 35(5), 313-316 (1999-07-20)
The inhibition of FeSO4 induced lipid peroxidation in rat liver by alcoholic extract of Rubia cordifolia and by one of its constituent rubiadin (1, 3-dihydroxy-2-methyl anthraquinone) (pure form) has been compared. Both have been found to inhibit lipid peroxidation in
Toxicon : official journal of the International Society on Toxinology, 51(8), 1409-1415 (2008-06-03)
Heterophyllaea pustulata (Rubiaceae), a South American genus, is a phototoxic shrub that grows in the Andean mountain range of the northwest of Argentina, popularly known as "cegadera". Animals that ingest the aerial parts of this plant suffer a typical primary
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