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Merck
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Documentos

69532

Supelco

Artemisinin

analytical standard

Sinónimos:

Arteannuin, Qinghaosu

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About This Item

Fórmula empírica (notación de Hill):
C15H22O5
Número de CAS:
63968-64-9
Peso molecular:
282.33
Número MDL:
MFCD00081057
Código UNSPSC:
41116107
ID de la sustancia en PubChem:
329761732
NACRES:
NA.24

grado

analytical standard

Nivel de calidad

100

Análisis

≥98.0% (TLC)

actividad óptica

[α]/D +75.0±3°, c = 0.5 in methanol

caducidad

limited shelf life, expiry date on the label

técnicas

HPLC: suitable
gas chromatography (GC): suitable

mp

156-157 °C (lit.)

aplicaciones

food and beverages

formato

neat

cadena SMILES

C[C@@H]1CC[C@H]2[C@@H](C)C(=O)O[C@@H]3OC4(C)CC[C@@H]1[C@@]23OO4

InChI

1S/C15H22O5/c1-8-4-5-11-9(2)12(16)17-13-15(11)10(8)6-7-14(3,18-13)19-20-15/h8-11,13H,4-7H2,1-3H3/t8-,9-,10+,11+,13-,14-,15-/m1/s1

Clave InChI

BLUAFEHZUWYNDE-NNWCWBAJSA-N

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Aplicación

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

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Certificados de análisis (COA)

Lot/Batch Number
BCCL5333
BCCJ2747
BCCH8866
BCCF6312
BCCD7493

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Pamela J Weathers et al.
Journal of ethnopharmacology, 153(3), 732-736 (2014-03-26)
The Chinese have used Artemisia annua as a tea infusion to treat fever for >2000 years. The active component is artemisinin. Previously we showed that when compared to mice fed an equal amount of pure artemisinin, a single oral dose
C Wongsrichanalai et al.
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 19(10), 908-916 (2013-09-17)
Following a decade-long scale up of malaria control through vector control interventions, the introduction of rapid diagnostic tests and highly efficacious Artemisinin-based Combination Therapy (ACT) along with other measures, global malaria incidence declined significantly. The recent development of artemisinin resistance
Benjamin J Visser et al.
Expert opinion on pharmacotherapy, 15(15), 2219-2254 (2014-08-12)
Chemotherapy of malaria has become a rapidly changing field. Less than two decades ago, treatment regimens were increasingly bound to fail due to emerging drug resistance against 4-aminoquinolines and sulfa compounds. By now, artemisinin-based combination therapies (ACTs) constitute the standard
Victor M Ye et al.
Biotechnology journal, 7(1), 20-33 (2011-10-25)
Driven by requirements for sustainability as well as affordability and efficiency, metabolic engineering of plants and microorganisms is increasingly being pursued to produce compounds for clinical applications. This review discusses three such examples of the clinical relevance of metabolic engineering:
Rick M Fairhurst et al.
The American journal of tropical medicine and hygiene, 87(2), 231-241 (2012-08-03)
Artemisinin-based combination therapies are the most effective drugs to treat Plasmodium falciparum malaria. Reduced sensitivity to artemisinin monotherapy, coupled with the emergence of parasite resistance to all partner drugs, threaten to place millions of patients at risk of inadequate treatment
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