62862

Dodecilsulfatosódico

≥90% ((Assay))

• Sinónimos: Dodecil sulfato de sodio, Dodecil sulfato sodium salt, Lauril sulfato sodium salt, Laurilsulfato de sodio, SDS
• Fórmula lineal: CH₃(CH₂)₁₁OSO₃Na
• Número de CAS: 151-21-3
• Peso molecular: 288.38
• Beilstein: 3599286
• Número CE: 205-788-1
• Número MDL: MFCD00036175
• Código UNSPSC: 12161900
• eCl@ss: 39093306
• ID de la sustancia en PubChem: 57651912
• NACRES: NA.21

Propiedades

• descripción: anionic; 62
• Nivel de calidad: 100
• Ensayo: ≥90% ((Assay))
• mol peso: 288.38 g/mol
• técnicas: LC/MS: suitable; electrophoresis: suitable; protein quantification: suitable
• mp: 204-207 °C (lit.)
• solubilidad: water: soluble
• HLB: 40
• cadena SMILES: [Na+].CCCCCCCCCCCCOS([O-])(=O)=O
• InChI: 1S/C12H26O4S.Na/c1-2-3-4-5-6-7-8-9-10-11-12-16-17(13,14)15;/h2-12H2,1H3,(H,13,14,15);/q;+1/p-1
• Clave InChI: DBMJMQXJHONAFJ-UHFFFAOYSA-M

Descripción

Descripción general

Sodium dodecyl sulfate (SDS), also known as sodium lauryl sulfate (SLS), has an alkyl tail of 12 carbon atoms attached to a sulfate group. It is an anionic surfactant due to the negative charge of its sulfate group.[1]

Aplicación

Detergente aniónico.

Sodium dodecyl sulfate has been used:

• to prepare Chit for coating the Janus micromotors for the synthesis of magnesium (Mg)-based micromotors[2]
• as a component in low salt lysis buffer to lyse the edible bird’s nest (EBN) treated cells for western blot analysis[3]
• in the preparation of decellularizing solution to scale down and decellularize skin fragments[4]

Acciones bioquímicas o fisiológicas

Sodium dodecyl sulfate (SDS) is frequently used as an ingredient in a wide range of products, including pharmaceuticals, and product formulations. It is broadly used in several applications including electrophoresis for the separation of proteins and as an organic template for preparing periodic mesoporous organosilica nanospheres. SDS is also used in the solubilization of proteins and lipids, as well as drugs, dispersion of functionalized carbon nanotubes and graphene sheets, and gas hydrate formation.[1] It is commonly used for the quick disruption of biological membranes. Due to its ability to disrupt the tissue architecture, SDS is preferred in several nucleic acid purification reagents. SDS has very low solubility in high salt, and chaotropic solutions and is readily precipitable in the presence of potassium salts, so it is usually not added to guanidinium buffers.[5]

Características y beneficios

• Assay: ≥90%
• Suitable for LC/MS, electrophoresis, and protein quantification
• Inhibits RNase and deoxyribonuclease (DNase) activity[5]

Información de seguridad

• Pictogramas: GHS02,GHS05,GHS07
• Palabra de señalización: Danger
• Frases de peligro: H228,H302 + H332,H315,H318,H335,H412
• Consejos de prudencia: P210 - P273 - P280 - P301 + P312 - P304 + P340 + P312 - P305 + P351 + P338
• Clasificaciones de peligro: Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Dam. 1 - Flam. Sol. 2 - Skin Irrit. 2 - STOT SE 3
• Órganos de actuación: Respiratory system
• Código de clase de almacenamiento: 4.1B - Flammable solid hazardous materials
• Clase de riesgo para el agua (WGK): WGK 2
• Punto de inflamabilidad (°F): 338.0 °F
• Punto de inflamabilidad (°C): 170 °C
• Equipo de protección personal: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges