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47673

Sigma-Aldrich

Formaldehído solution

tested according to Ph. Eur.

Sinónimos:

Formalina

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About This Item

Fórmula lineal:
HCHO
Número de CAS:
50-00-0
Peso molecular:
30.03
Beilstein:
1209228
Número MDL:
MFCD00003274
Código UNSPSC:
12352114
ID de la sustancia en PubChem:
329757334
NACRES:
NA.25

Agency

USP/NF
tested according to Ph. Eur.

Nivel de calidad

200

densidad de vapor

1.03 (vs air)

presión de vapor

52 mmHg ( 37 °C)

formulario

liquid

temp. de autoignición

572 °F

contiene

9.0-15.0 % (v/v) methanol as stabilizer

concentración

25-50%

solubilidad

water: soluble

densidad

1.09 g/mL at 25 °C (lit.)

idoneidad

suitable for manufacturing use (Laboratory chemicals)

cadena SMILES

[H]C([H])=O

InChI

1S/CH2O/c1-2/h1H2

Clave InChI

WSFSSNUMVMOOMR-UHFFFAOYSA-N

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Aplicación

Formaldehyde solution has been used to fix labeled cells during flow cytometry.

Acciones bioquímicas o fisiológicas

Formaldehyde is the simplest aldehyde that denatures the bihelical regions of RNA and converts the polynucleotides into random coils. It is a genotoxic substance that significantly induces DNA-protein crosslinks (DPC), sister-chromatid exchanges, micronuclei formation and leads to cytotoxicity. It also induces tumors in the nasal epithelium of rats and supposed to be a human carcinogen.

Precaución

may become turbid on storage

Palabra de señalización

Danger

Clasificaciones de peligro

Acute Tox. 2 Inhalation - Acute Tox. 3 Dermal - Acute Tox. 3 Oral - Carc. 1B - Eye Dam. 1 - Flam. Liq. 3 - Muta. 2 - Skin Corr. 1B - Skin Sens. 1 - STOT SE 1 - STOT SE 3

Órganos de actuación

Eyes,Central nervous system, Respiratory system

Código de clase de almacenamiento

3 - Flammable liquids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

133.0 °F - closed cup

Punto de inflamabilidad (°C)

56.11 °C - closed cup

Equipo de protección personal

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

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Certificados de análisis (COA)

Lot/Batch Number
BCCL7378
BCCL8065
BCCL5543
BCCK8902
BCCL0858

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J L Wilson et al.
Journal of immunology (Baltimore, Md. : 1950), 163(12), 6365-6370 (1999-12-10)
NK cells have the capacity to spontaneously kill tumor cell lines, in particular cell lines of hemopoietic origin. In contrast, they do not generally kill nontransformed autologous cells. However, here we demonstrate that short-term activated polyclonal human NK cells, as
O Merk et al.
Environmental and molecular mutagenesis, 32(3), 260-268 (1998-11-14)
Formaldehyde (FA) is a genotoxic substance, induces tumors in the nasal epithelium of rats, and is suspected to be a human carcinogen. As a primary DNA lesion, FA induces DNA-protein crosslinks (DPC) and the formation of DPC has been used
Dependence of the sedimentation coefficient on molecular weight of RNA after reaction with formaldehyde.
H Boedtker
Journal of molecular biology, 35(1), 61-70 (1968-07-14)
Cindy S Ma et al.
The Journal of experimental medicine, 205(7), 1551-1557 (2008-07-02)
Hyper-immunoglobulin E syndrome (HIES) is a primary immune deficiency characterized by abnormal and devastating susceptibility to a narrow spectrum of infections, most commonly Staphylococcus aureus and Candida albicans. Recent investigations have identified mutations in STAT3 in the majority of HIES
Stephanie Belloc et al.
Fertility and sterility, 101(6), 1588-1593 (2014-04-03)
To evaluate sperm DNA fragmentation in normozoospermic male partners of couples undergoing infertility evaluation. Retrospective cohort study. Clinical andrology laboratory. A total of 1,974 consecutive normozoospermic men selected from a larger cohort of 4,345 consecutive, nonazoospermic men presenting for infertility
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