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42612

Supelco

Honokiol

analytical standard

Sinónimos:

5,3′-Diallyl-2,4′-dihydroxybiphenyl, NSC 293100

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About This Item

Fórmula empírica (notación de Hill):
C18H18O2
Número de CAS:
35354-74-6
Peso molecular:
266.33
Número MDL:
MFCD00016674
Código UNSPSC:
85151701
ID de la sustancia en PubChem:
329756248
NACRES:
NA.24

grado

analytical standard

Nivel de calidad

100

Análisis

≥98.0% (HPLC)

caducidad

limited shelf life, expiry date on the label

técnicas

HPLC: suitable
gas chromatography (GC): suitable

aplicaciones

food and beverages

formato

neat

temp. de almacenamiento

2-8°C

cadena SMILES

Oc1ccc(cc1CC=C)-c2cc(CC=C)ccc2O

InChI

1S/C18H18O2/c1-3-5-13-7-9-18(20)16(11-13)14-8-10-17(19)15(12-14)6-4-2/h3-4,7-12,19-20H,1-2,5-6H2

Clave InChI

FVYXIJYOAGAUQK-UHFFFAOYSA-N

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Aplicación

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Acciones bioquímicas o fisiológicas

Honokiol is a natural biphenyl neolignan from magnolia extract. It is antiangiogenic, antitumor, and anxiolytic.

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Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Pictogramas

CorrosionEnvironment
GHS05,GHS09

Palabra de señalización

Danger

Frases de peligro

H318,H411

Clasificaciones de peligro

Aquatic Chronic 2 - Eye Dam. 1

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

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Certificados de análisis (COA)

Lot/Batch Number
BCCL2706
BCCK6578
BCCH3232
BCCH7517
BCCF9212

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Ankit Kumar et al.
Future medicinal chemistry, 5(7), 809-829 (2013-05-09)
Honokiol (3,5-di-(2-propenyl)-1,1-biphenyl-2,2-diol) is a natural bioactive neolignan isolated from the genus Magnolia. In recent studies, honokiol has been observed to have anti-angiogenic, anticancer, anti-inflammatory, neuroprotective and GABA-modulating properties in vitro and in preclinical models. Honokiol and its analogs target multiple
Haiquan Wang et al.
Neuropharmacology, 86, 9-21 (2014-06-29)
Recently, increasing evidence has shown that cell cycle activation is a key factor of neuronal death and neurological dysfunction after traumatic brain injury (TBI). This study aims to investigate the effects of Honokiol, a cell cycle inhibitor, on attenuating the
Wei-Zhe Liang et al.
Chemico-biological interactions, 221, 13-23 (2014-08-12)
Honokiol, an active constituent of oriental medicinal herb Magnolia officinalis, caused Ca(2+) mobilization and apoptosis in different cancer cells. In vivo, honokiol crossed the blood-brain or -cerebrospinal fluid barrier, suggesting that it may be an effective drug for the treatment
Eun-Ryeong Hahm et al.
The Prostate, 74(4), 408-420 (2013-12-18)
We have shown previously that honokiol (HNK), a bioactive component of the medicinal plant Magnolia officinalis, inhibits growth of human prostate cancer cells in vitro and in vivo. However, the effect of HNK on androgen receptor (AR) signaling has not
Ying-Jiun Lai et al.
Journal of cellular biochemistry, 115(11), 1888-1899 (2014-06-07)
Honokiol is a small biphenolic compound, which exerts antitumor activities; however, the precise mechanism of honokiol-induced apoptosis in the human colorectal cancer cells remains unclear. Here, we show that survivin and p53 display the opposite role on the regulation of
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