37019

Atropine

analytical standard

• Sinónimos: Hyoscyamine, Tropine tropate, endo-(±)-α-(Hydroxymethyl)benzeneacetic acid 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester
• Fórmula empírica (notación de Hill): C₁₇H₂₃NO₃
• Número de CAS: 51-55-8
• Peso molecular: 289.37
• Beilstein: 91260
• Número CE: 200-104-8
• Número MDL: MFCD00022622
• Código UNSPSC: 85151701
• ID de la sustancia en PubChem: 329755584
• NACRES: NA.24

Propiedades

• grado: analytical standard
• caducidad: limited shelf life, expiry date on the label
• técnicas: HPLC: suitable; gas chromatography (GC): suitable
• aplicaciones: cleaning products; cosmetics; food and beverages; personal care
• formato: neat
• temp. de almacenamiento: −20°C
• cadena SMILES: CN1[C@H]2CC[C@@H]1C[C@@H](C2)OC(=O)C(CO)c3ccccc3
• InChI: 1S/C17H23NO3/c1-18-13-7-8-14(18)10-15(9-13)21-17(20)16(11-19)12-5-3-2-4-6-12/h2-6,13-16,19H,7-11H2,1H3/t13-,14+,15+,16?
• Clave InChI: RKUNBYITZUJHSG-SPUOUPEWSA-N
• Información sobre el gen: human ... CHRM1(1128) , CHRM2(1129) , CHRM3(1131)

Descripción

Descripción general

Atropine is an antimuscarinic drug, which is classified under the tropane alkaloid family of compounds.

Atropine is an antimuscarinic drug, which is classified under the tropane alkaloid family of compounds.
For the analysis of the phytotoxins.

Aplicación

Atropine may be used as a reference standard for the determination of atropine in:

• Blood samples by liquid chromatography combined with electrospray ionization-triple quadrupole mass spectrometry (LC-ESI-MS/MS).
• Hair samples by ultra-high performance liquid chromatography-high resolution mass spectrometry (UHPLC-HRMS) consisting of single-stage Orbitrap MS system with ESI interface.
• Oganic buckwheat (Fagopyron esculentum L.) products by UHPLC-MS/MS.
• Plant materials by liquid-liquid extraction and EXtrelut^® column clean-up followed by analysis using gas chromatography (GC) coupled with flame ionization detector (FID) and MS.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Atropine may be used as a reference standard for the determination of atropine in:

• Blood samples by liquid chromatography combined with electrospray ionization-triple quadrupole mass spectrometry (LC-ESI-MS/MS).
• Hair samples by ultra-high performance liquid chromatography-high resolution mass spectrometry (UHPLC-HRMS) consisting of single-stage Orbitrap MS system with ESI interface.
• Oganic buckwheat (Fagopyron esculentum L.) products by UHPLC-MS/MS.
• Plant materials by liquid-liquid extraction and EXtrelut^® column clean-up followed by analysis using gas chromatography (GC) coupled with flame ionization detector (FID) and MS.

Acciones bioquímicas o fisiológicas

Competitive nonselective antagonist at central and peripheral muscarinic acetylcholine receptors.

Reconstitución

Dried down, ~100μg/mL after reconstitution with 1 mL of water

Nota de análisis

purity : ≥96.0% (HPLC)

Información legal

Extrelut is a registered trademark of Merck KGaA, Darmstadt, Germany

Información de seguridad

• Pictogramas: GHS06
• Palabra de señalización: Danger
• Frases de peligro: H300 + H330
• Consejos de prudencia: P260 - P264 - P271 - P284 - P304 + P340 + P310 - P403 + P233
• Clasificaciones de peligro: Acute Tox. 2 Inhalation - Acute Tox. 2 Oral
• Código de clase de almacenamiento: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable