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Merck
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09569

Supelco

Span® 80

greener alternative

suitable for GC

Sinónimos:

Sorbitan monooleate, Span® 80

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About This Item

Fórmula empírica (notación de Hill):
C24H44O6
Número de CAS:
1338-43-8
Peso molecular:
428.60
Beilstein:
8172514
Número CE:
215-665-4
Número MDL:
MFCD00080948
Código UNSPSC:
12000000
ID de la sustancia en PubChem:
329748773
NACRES:
NA.21

descripción

non-ionic

Nivel de calidad

100

mol peso

428.60 g/mol

características de los productos alternativos más sostenibles

Use of Renewable Feedstocks
Design for Degradation
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

técnicas

LPLC: suitable
gas chromatography (GC): suitable
protein quantification: suitable

índice de refracción

n20/D 1.48 (lit.)

valor de HLB

4.6±0.1

densidad

0.99 g/mL at 20 °C
0.986 g/mL at 25 °C (lit.)

categoría alternativa más sostenible

Aligned,

cadena SMILES

[H][C@@](O)(COC(=O)CCCCCCC\C=C/CCCCCCCC)[C@H]1OC[C@H](O)[C@H]1O

InChI

1S/C24H44O6/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-22(27)29-19-21(26)24-23(28)20(25)18-30-24/h9-10,20-21,23-26,28H,2-8,11-19H2,1H3/b10-9-/t20-,21+,23+,24+/m0/s1

Clave InChI

NWGKJDSIEKMTRX-AAZCQSIUSA-N

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Descripción general

We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Green Chemistry. This product is biodegradable surfactant, thus aligns with "Use of Renewable Feedstocks" and "Design for Degradation" principles of Green Chemistry, and belongs to "12 principles aligned" category of our greener alternatives.

Aplicación

A non-ionic surfactant that can be used to form oil-in-water emulsions and in combination with low HLB surfactants can form water-in-oil emulsions. EPA approved oil spill dispersant.

Información legal

Span is a registered trademark of Croda International PLC

Código de clase de almacenamiento

10 - Combustible liquids

Clase de riesgo para el agua (WGK)

WGK 1

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Equipo de protección personal

Eyeshields, Gloves

Choose from one of the most recent versions:

Certificados de análisis (COA)

Lot/Batch Number
BCCM0986
BCCK8479
BCCJ9835
BCCG6479
BCCD4633

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If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

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Sigma-Aldrich

S3386

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Sigma-Aldrich

85547

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TWEEN® 65

Sigma-Aldrich

P3190

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Ethyl heptanoate ReagentPlus®, 99%

Sigma-Aldrich

112364

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Polysorbate 60 tested according to Ph. Eur.

Sigma-Aldrich

95754

Polysorbate 60

Hoang Hirschberg et al.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 46(1-2), 1-7 (2012-02-15)
In the search for an optimal approach for the transcutaneous immunization (TCI) of hepatitis B surface antigen (HBsAg), two vesicle formulations, L595 vesicles (composed of sucrose-laurate ester and octaoxyethylene-laurate ester) and sPC vesicles (composed of soybean-phosphatidylcholine and Span-80) were prepared
Faiyaz Shakeel et al.
Drug development and industrial pharmacy, 40(9), 1240-1245 (2013-07-11)
Abstract For the development of an effective self-nanoemulsifying drug delivery system (SNEDDS) of poorly soluble drugs, the knowledge of the solubility in its oil phase and SNEDDS are one of the most important factors to avoid possibility of drug to
Daniela S Bernardi et al.
Journal of nanobiotechnology, 9, 44-44 (2011-09-29)
Nanoemulsions have practical application in a multitude of commercial areas, such as the chemical, pharmaceutical and cosmetic industries. Cosmetic industries use rice bran oil in sunscreen formulations, anti ageing products and in treatments for skin diseases. The aim of this
Keita Hayashi et al.
Colloids and surfaces. B, Biointerfaces, 106, 258-264 (2013-02-26)
We have focused on the interaction between the Span 80 vesicle and phospholipid vesicle (liposome). The Span 80 vesicle was mixed with a phospholipid vesicle (liposome), used as a simplified model of plasma membrane. From calcein leakage experiments, it was
Keita Hayashi et al.
International journal of biological sciences, 9(2), 142-148 (2013-02-16)
Span 80 (sorbitan monooleate) vesicles behaved differently from conventional phospholipid vesicles (liposomes) because the former had a more fluid interface. After doxorubicin hydrochloride (DOX) was encapsulated into the Span 80 vesicle (loading efficiency: 63 %), DOX-loaded Span 80 vesicles (DVs)
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