The expression level of the beta2 and alpha2 adrenergic receptors have not been determined for the INS-1 832/13 Rat Insulinoma Cell Line.
SCC207
INS-1 832/13 Rat Insulinoma Cell Line
Rat
Sinónimos:
INS1 832/13, INS-1 (832/13), INS 832/13, 832/13, 832/13 INS-1
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1 VIAL
1110,00 €
1110,00 €
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1 VIAL
1110,00 €
About This Item
Código UNSPSC:
41106514
eCl@ss:
32011203
NACRES:
NA.81
1110,00 €
Póngase en contacto con nuestro Servicio de Atención al Cliente para disponibilidad
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Nombre del producto
INS-1 832/13 Rat Insulinoma Cell Line, INS-1 832/13 rat insulinoma cell line is a useful model for insulin secretion regulation and pancreatic islet beta-cell function studies.
origen biológico
rat
técnicas
cell culture | mammalian: suitable
Condiciones de envío
ambient
Descripción general
Glucose-stimulated insulin secretion (GSIS) is potentiated by pancreatic beta cells and is critical to the physiological control of blood glucose levels. Insulin secretion is impaired in type 2 diabetes, and insight into the mechanisms and regulation of insulin secretion is fundamental to understanding the roles of beta cells in metabolic disease.
Descripción línea celular
Cancer Cells
Aplicación
INS-1 832/13 rat insulinoma cell line is a useful model for insulin secretion regulation and pancreatic islet beta-cell function studies.
Research Category
Metabolism
Metabolism
Research Sub Category
Diabetes
Diabetes
This product is intended for sale and sold solely to academic institutions for internal academic research use per the terms of the “Academic Use Agreement” as detailed in the product documentation. For information regarding any other use, please contact [email protected].
Calidad
• Each vial contains ≥ 1X10⁶ viable cells.
• Cells are tested negative for infectious diseases by a Mouse/Rat Comprehensive CLEAR panel by Charles River Animal Diagnostic Services.
• Cells are verified to be of rat origin and negative for inter-species contamination from mouse, chinese hamster, Golden Syrian hamster, human and non-human primate (NHP) as assessed by a Contamination CLEAR panel by Charles River Animal Diagnostic Services.
• Cells are negative for mycoplasma contamination.
• Cells are tested negative for infectious diseases by a Mouse/Rat Comprehensive CLEAR panel by Charles River Animal Diagnostic Services.
• Cells are verified to be of rat origin and negative for inter-species contamination from mouse, chinese hamster, Golden Syrian hamster, human and non-human primate (NHP) as assessed by a Contamination CLEAR panel by Charles River Animal Diagnostic Services.
• Cells are negative for mycoplasma contamination.
Almacenamiento y estabilidad
Store in liquid nitrogen. The cells can be cultured for at least 10 passages after initial thawing without significantly affecting the cell marker expression and functionality.
Cláusula de descargo de responsabilidad
This product contains genetically modified organisms (GMO). Within the EU GMOs are regulated by Directives 2001/18/EC and 2009/41/EC of the European Parliament and of the Council and their national implementation in the member States respectively. This legislation obliges {HCompany} to request certain information about you and the establishment where the GMOs are being handled. Click here for Enduser Declaration (EUD) Form.
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Código de clase de almacenamiento
12 - Non Combustible Liquids
Clase de riesgo para el agua (WGK)
WGK 1
Punto de inflamabilidad (°F)
Not applicable
Punto de inflamabilidad (°C)
Not applicable
Certificados de análisis (COA)
Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»
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Cell metabolism, 33(4), 804-817 (2020-12-16)
Metabolic fuels regulate insulin secretion by generating second messengers that drive insulin granule exocytosis, but the biochemical pathways involved are incompletely understood. Here we demonstrate that stimulation of rat insulinoma cells or primary rat islets with glucose or glutamine + 2-aminobicyclo-(2,2,1)-heptane-2-carboxylic
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Hej, we are considering to purchase your INS-1 cell line. Is it known, if it expresses beta2 and alfa2 adrenergic receptors? Thank you!
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