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MADKMAG-71K

Millipore

MILLIPLEX® Mouse Adipokine Magnetic Bead Panel - Endocrine Multiplex Assay

The analytes available for this multiplex kit are: IL-6, Insulin, Leptin, MCP-1, PAI-1 (Total), Resistin, TNF-α.

Sinónimos:

luminex mouse adipokine multiplex kit, luminex mouse obesity multiplex kit, millipore mouse metabolic syndrome disease multiplex, mouse metabolism diabetes immunoassay panel

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About This Item

Código UNSPSC:
12161503
eCl@ss:
32161000
NACRES:
NA.84

To order a Milliplex® kit, please search for your analyte of interest.

Nivel de calidad

reactividad de especies

mouse

fabricante / nombre comercial

Milliplex®

assay range

accuracy: 77-92%
standard curve range: 12.2-50,000 pg/mL

técnicas

multiplexing: suitable

método de detección

fluorometric (Luminex xMAP)

Condiciones de envío

wet ice

Descripción general

The discovery of leptin secretion from adipocytes in 1994 led to the recognition that white adipose tissue is involved in a variety of metabolic and physiological processes. Adipocytes secrete several hormones called adipokines with functions that include appetite and energy balance, insulin sensitivity and lipid metabolism.

MILLIPLEX® Mouse Adipokine Panel is a 7-plex kit to be used for the simultaneous quantification of any or all of the following analytes in mouse serum and plasma samples: IL-6, Insulin, Leptin, MCP-1, PAI-1 Total, Resistin and TNFα. This kit uses a 96-well format, contains a lyophilized standard cocktail, two internal assay quality controls and can measure up to 38 samples in duplicate.

The Luminex® xMAP® platform uses a magnetic bead immunoassay format for ideal speed and sensitivity to quantitate multiple analytes simultaneously, dramatically improving productivity while conserving valuable sample volume.

Panel Type: Metabolism

Especificidad

Cross Reactivty
Each antibody pair in a panel is highly specific and displays insignificant cross-reactivity to other analytes in the panel.

Aplicación

  • Analytes: IL-6, Insulin, Leptin, MCP-1 (CCL2), PAI-1 (Total), Resistin, TNF-α
  • Recommended Sample Type: Mouse serum and plasma
  • Recommended Sample Dilution: 10 μL per well of undilute d serum or plasma
  • Assay Run Time: Overnight (16-18 hours) at 2-8°C.
  • Research Category: Metabolism
  • Research Subcategory: Endocrine, Obesity, Metabolic Disorders

Características y beneficios

Design your multiplex kit by choosing available analytes within this panel.

Otras notas

Sensitivity: Please see kit protocol for sensitive’s of individual biomarkers.

Información legal

Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Pictogramas

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Palabra de señalización

Warning

Clasificaciones de peligro

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Skin Sens. 1

Código de clase de almacenamiento

10 - Combustible liquids


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Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Obesity causes white adipose tissue (WAT) inflammation and insulin resistance in some, but not all individuals. Here, we used a mouse model of early postnatal overfeeding to determine the role of neonatal nutrition in lifelong WAT inflammation and metabolic dysfunction.
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Molecular and cellular endocrinology, 480, 1-11 (2018-10-06)
Previously, apoE-derived ABCA1 agonist peptides have been shown to possess anti-atherosclerotic and possibly antidiabetic properties. Here we assessed the in vitro and in vivo actions of a second generation of ABCA1 peptide agonists, CS6253 and T6991-2, on glucose homeostasis. The
Sara A DiVall et al.
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Infertility associated with obesity is characterized by abnormal hormone release from reproductive tissues in the hypothalamus, pituitary, and ovary. These tissues maintain insulin sensitivity upon peripheral insulin resistance. Insulin receptor signaling may play a role in the dysregulation of gonadotropin-releasing
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Journal of the American Association for Laboratory Animal Science : JAALAS, 54(6), 708-717 (2015-12-04)
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Contenido relacionado

Multiplex immunoassays, such as MILLIPLEX® multiplex metabolic assays, are critical in metabolic syndrome research because they provide a full picture of the different conditions related to it, like diabetes and obesity, as well as save time and sample volume.

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