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MAB5416

Sigma-Aldrich

Anti-Glutamate Receptor 3 Antibody, clone 3B3

clone 3B3, Chemicon®, from mouse

Sinónimos:

AMPA-selective glutamate receptor 3, Glutamate receptor ionotropic, AMPA 3, glutamate receptor 3, glutamate receptor C, glutamate receptor subunit 3, glutamate receptor, ionotrophic, AMPA 3

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About This Item

Código UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

origen biológico

mouse

Nivel de calidad

100

forma del anticuerpo

purified antibody

tipo de anticuerpo

primary antibodies

clon

3B3, monoclonal

reactividad de especies

monkey, mouse, human

reactividad de especies (predicha por homología)

rat

fabricante / nombre comercial

Chemicon®

técnicas

immunocytochemistry: suitable
immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
western blot: suitable

isotipo

IgG1κ

Nº de acceso NCBI

NM_000840.2

Nº de acceso UniProt

P42263

Condiciones de envío

dry ice

modificación del objetivo postraduccional

unmodified

Información sobre el gen

human ... GRIA3(2892)

Descripción general

AMPA receptors mediate fast synaptic current at most excitatory synapses, with stoichiometry characterized by subtype composition.There are four types of AMPA selective GluR subunits (GluR1, GluR2, GluR3 and GluR4). Tetrameric or pentameric combinations of different subunits contributes to the functional diversity of AMPA receptors. The insertion or removal of GluR1/GluR4 oligomeric channels from postsynaptic membranes appears to be LTP/LTD activity dependent while GluR2/GluR3 oligomers are continuously cycling. Millipore’s anti-GluR2/3 antibody is useful for localizing expression of GluR2/GluR3 receptor assemblies in the PSD.

Especificidad

Reacts with Glutamate Receptor 3 (GluR3). No cross reactivity with GluR2.

Inmunógeno

Fusion protein, N-terminus of GluR3

Aplicación

Anti-Glutamate Receptor 3 Antibody, clone 3B3 is an antibody against Glutamate Receptor 3 for use in WB, IC, IH, IH(P).
Immunohistochemistry: A previous lot of this antibody was used in IH.

Optimal working dilutions must be determined by end user.

Calidad

Western Blot Analysis: A previous lot of this antibody was used in WB.

Descripción de destino

~ 110 kDa

Forma física

Format: Purified
Liquid in PBS. Contains no preservative.

Nota de análisis

Control
Brain

Hippocampal tissue

Otras notas

2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research

Información legal

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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Código de clase de almacenamiento

12 - Non Combustible Liquids

Clase de riesgo para el agua (WGK)

WGK 2

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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David Bartolomé-Martín et al.
Journal of cell science, 125(Pt 2), 422-434 (2012-02-15)
Following the exocytosis of neurotransmitter-containing synaptic vesicles, endocytosis is fundamental to re-establishing conditions for synaptic transmission. As there are distinct endocytotic pathways that each differ in their efficiency to generate releasable synaptic vesicles, we used the dye FM1-43 to track
Evolutionarily conserved pattern of AMPA receptor subunit glycosylation in Mammalian frontal cortex.
Tucholski, J; Pinner, AL; Simmons, MS; Meador-Woodruff, JH
Testing null
Sven Jarius et al.
Journal of neuroinflammation, 11, 206-206 (2014-12-17)
We report on a serum autoantibody associated with cerebellar ataxia. Immunohistochemical studies of sera from four patients referred for autoantibody testing revealed binding of high-titer (up to 1:5,000) IgG antibodies, mainly IgG1, to the molecular layer, Purkinje cell layer, and
Janusz Tucholski et al.
Schizophrenia research, 146(1-3), 177-183 (2013-03-07)
Numerous studies have demonstrated brain region- and subunit-specific abnormalities in the expression of subunits of the AMPA subtype of glutamate receptors in schizophrenia. In addition, abnormalities in the expression of proteins that regulate the forward trafficking of AMPA receptors through
Distinct perisynaptic and synaptic localization of NMDA and AMPA receptors on ganglion cells in rat retina.
Zhang, J; Diamond, JS
The Journal of Comparative Neurology null
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