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HAGP1MAG-12K

Millipore

MILLIPLEX® Human Angiogenesis/Growth Factor Magnetic Bead Panel - Cancer Multiplex Assay

Angiogenesie Bead-Based Multiplex Assays using the Luminex technology enables the simultaneous analysis of multiple angiogenic biomarkers in human serum, plasma and cell culture samples.

Sinónimos:

human oncology growth factor immunoassay panel, luminex human cancer angiogenesis growth factor multiplex assay, millipore human cancer growth factor protein multiplex kit

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About This Item

Código UNSPSC:
12161503
eCl@ss:
32161000
NACRES:
NA.84
To order a Milliplex® kit, please search for your analyte of interest.
Design And Price Your Kit

Nivel de calidad

200

reactividad de especies

human

fabricante / nombre comercial

Milliplex®

assay range

accuracy: 42-131%
standard curve range: 1.4-1,000 pg/mL
(HB-EGF, IL-8, PLGF)
standard curve range: 13.7-10,000 pg/mL
(Angiopoietin-2, FGF-1, FGF-2, G-CSF, VEGF-A)
standard curve range: 137.2-100,000 pg/mL
(Leptin)
standard curve range: 2.7-2,000 pg/mL
(BMP-9, EGF, Endothelin-1)
standard curve range: 27.4-20,000 pg/mL
(Endoglin, Follistatin, HGF)
standard curve range: 6.9-5,000 pg/mL
(VEGF-C, VEGF-D)

técnicas

multiplexing: suitable

método de detección

fluorometric (Luminex xMAP)

Condiciones de envío

wet ice

Categorías relacionadas

Descripción general

Angiogenesis, the development of new vascular networks, is a key process in normal growth and development as well as in wound healing, with homeostasis maintained by a delicate balance of angiogenic factors and inhibitors. Consequently, insufficient, or excessive blood vessel growth underlies many diseases, including cardiovascular disease, diabetic ulcers, macular degeneration, and cancer. Angiogenesis plays a significant role in tumor growth and metastasis.

The MILLIPLEX® Human Angiogenesis / Growth Factor Panel 1 is to be used for the simultaneous quantification of any or all of the following 17 human angiogenesis and growth factor biomarkers in human plasma, serum samples and tissue/cell lysate and culture supernatant samples: Angiopoietin-2, BMP-9, EGF, Endoglin, Endothelin-1, FGF-1 (acidic FGF), FGF-2 (basic FGF), Follistatin, G-CSF, HB-EGF, HGF, IL-8, Leptin, PLGF, VEGF-A, VEGF-C and VEGF-D. This kit uses a 96-well format, contains a lyophilized standard cocktail, two internal assay quality controls and can measure up to 38 samples in duplicate.

The Luminex® xMAP® platform uses a magnetic bead immunoassay format for ideal speed and sensitivity to quantitate multiple analytes simultaneously, dramatically improving productivity while conserving valuable sample volume.

Panel Type: Circulating Cancer

Especificidad

Cross Reactivty
Cross-reactivity between the antibodies and any of the other analytes in this panel is non-detectable or negligible.

Aplicación

  • Analytes: Angiopoietin-2, BMP-9, EGF, Endoglin, Endothelin-1, FGF-1 (acidic FGF), FGF-2 (basic FGF), Follistatin, G-CSF, HB-EGF, HGF, IL-8, Leptin, PLGF, VEGF-A, VEGF-C, VEGF-D
  • Recommended Sample Type: Human serum, plasma, tissue/cell lysate or culture supernatants
  • Recommended Sample Dilution: 25 μL per well of a 1:3 dilution of plasma or serum; 25 μL cell culture supernatant per well, diluted with appropriate control medium as needed
  • Assay Run Time: Overnight (16-18 hours) at 2-8°C
  • Research Category: Cancer

Características y beneficios

Design your multiplex kit by choosing available analytes within this panel.

Envase

Everything you need in a single kit.

Almacenamiento y estabilidad

Recommended storage for kit components is 2 - 8°C.

Otras notas

Sensitivity: Refer to kit protocol for sensitivities of individual analytes.

Información legal

Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Palabra de señalización

Danger

Clasificaciones de peligro

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1 - STOT RE 2

Órganos de actuación

Respiratory Tract

Código de clase de almacenamiento

10 - Combustible liquids

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Visite la Librería de documentos

Kevin P Daly et al.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 32(1), 120-128 (2012-12-25)
Cardiac allograft vasculopathy (CAV), the major cause of late allograft loss after cardiac transplantation, results from donor-directed cellular and humoral alloimmune responses. Graft vascular endothelial cells (EC) are primary targets of these destructive responses, suggesting that factors associated with endothelial
Karen K Mestan et al.
The Journal of pediatrics, 185, 33-41 (2017-02-07)
To assess whether cord blood biomarkers associated with placental maternal vascular underperfusion (MVU) are predictive of bronchopulmonary dysplasia-associated pulmonary hypertension (BPD-PH). Premature infants enrolled in a longitudinal cohort study were randomly sampled from 4 gestational age strata (n?=?190, range 23-36
David G Belair et al.
Biomaterials science, 4(5), 819-825 (2016-03-25)
Platelets contain an abundance of growth factors that mimic the composition of the wound healing milieu, and platelet-derived VEGF in particular can negatively influence wound healing if unregulated. Here, we sought to capture and regulate the activity of VEGF factor
O E Olsen et al.
Blood cancer journal, 4, e196-e196 (2014-03-25)
Multiple myeloma is a malignancy of plasma cells predominantly located in the bone marrow. A number of bone morphogenetic proteins (BMPs) induce apoptosis in myeloma cells in vitro, and with this study we add BMP-9 to the list. BMP-9 has
Ruijin Shao et al.
Data in brief, 6, 135-142 (2016-02-10)
In this data, non-pregnant women during the menstrual cycle, women with normal intrauterine pregnancy (IUP), and women with tubal ectopic pregnancy (EP) after informed consent were included. The serum levels of 17β-estradiol, progesterone, testosterone, beta-human chorionic gonadotropin, interleukin (IL)-1β, IL-4
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