FCABS301A4

Milli-Mark^® Anti-dimethyl-Histone H3 (Lys9)-Alexa Fluor^™488 Antibody

Milli-Mark^®, from rabbit

• Sinónimos: H3 histone family, member T, histone 3, H3, histone cluster 3, H3
• Código UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Propiedades

• origen biológico: rabbit
• Nivel de calidad: 100
• conjugado: ALEXA FLUOR^™ 488
• forma del anticuerpo: purified immunoglobulin
• tipo de anticuerpo: primary antibodies
• clon: polyclonal
• reactividad de especies: human
• fabricante / nombre comercial: Milli-Mark^®
• técnicas: flow cytometry: suitable
• isotipo: IgG
• Nº de acceso NCBI: NP_003484
• Nº de acceso UniProt: Q16695
• Condiciones de envío: wet ice
• modificación del objetivo postraduccional: dimethylation (Lys9)
• Información sobre el gen: human ... H3C1(8350)

Descripción

Descripción general

Histone H3 is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N-terminal tail, H3 is involved with the structure of the nucleosomes of the ′beads on a string′ structure. The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of epigenetic modifications that influence cellular processes. These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine amino acids and the phosphorylation of serine or threonine.

Especificidad

Antibody recognizes human Histone H3 dimethylated on lysine 9.

Inmunógeno

Epitope: Methylated at Lys9dimethylated Lys 9 of Human Histone H3

KLH-conjugated, 2X-branched synthetic peptide corresponding to dimethyl-lysine at residue 9 of human Histone H3.

Aplicación

Milli-Mark Anti-dimethyl-Histone H3 (Lys9)-Alexa Fluor488 Antibody detects level of dimethyl-Histone H3 (Lys9)-Alexa Fluor488 & has been published & validated for use in FC.

Research Category
Epigenetics & Nuclear Function

Research Sub Category
Histones

Calidad

Evaluated by flow cytometry using HeLa cells

Descripción de destino

15.5 kDa Calculated

Forma física

Protein A purified

Purified rabbit polyclonal IgG conjugated to Alexa Fluor 488 in PBS with 0.1% sodium azide and 15 mg/mL BSA

Almacenamiento y estabilidad

Maintain refrigerated at 2-8°C protected from light for up to 6 months from date of receipt.

Nota de análisis

Control
HeLa Cells

Información legal

ALEXA FLUOR is a trademark of Life Technologies

MILLI-MARK is a registered trademark of Merck KGaA, Darmstadt, Germany

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 12 - Non Combustible Liquids
• Clase de riesgo para el agua (WGK): WGK 2
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable