IgM constitutes about 10% of serum immunoglobulins. IgM antibody is prominent in early immune responses to most antigens and predominates in certain antibody responses such as ′natural′ blood group antibodies. IgM (with IgD) is the major immunoglobulin expressed on the surface of B cells. The gene for the mu constant region contains four domains separated by short intervening sequences.
Especificidad
The antibody reacts with the heavy chain of mouse IgM as demonstrated by ELISA and flow cytometry. Minimal cross reactivity with human immunoglobulins.
Inmunógeno
Prepared from mouse IgM µ chain. Pooled antisera from goats hyperimmunized with mouse IgM paraproteins.
Aplicación
Goat anti-Mouse IgM µ chain Antibody, Cy5 conjugate, Species Adsorbed detects level of Mouse IgM µ chain & has been published & validated for use in ELISA & IF.
Immunofluorescence: ≤0.1 μg/106 cells ELISA
Optimal working dilutions must be determined by the end user.
Research Category Secondary & Control Antibodies
Research Sub Category Secondary Antibodies Adsorbed for Dual Labeling
Fragment Specific Secondary Antibodies
Adsorbente de anticuerpos
Absorbed for mouse IgG1, IgG2a, IgG2b, IgG3 and IgA, pooled human sera and purified human paraproteins. Minimal cross reactivity with human immunoglobulins.
Forma física
Affinity Chromatography
Purified by affinity chromatography on mouse IgM covalently linked to agarose. Liquid in 1.0 mL PBS/NaN3.
Almacenamiento y estabilidad
Maintain refrigerated at 2°-8°C under sterile conditions for up to twelve months from date of receipt. Do not freeze.
Información legal
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Cláusula de descargo de responsabilidad
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Código de clase de almacenamiento
10 - Combustible liquids
Clase de riesgo para el agua (WGK)
WGK 2
Punto de inflamabilidad (°F)
Not applicable
Punto de inflamabilidad (°C)
Not applicable
Certificados de análisis (COA)
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