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AB1526

Sigma-Aldrich

Anti-Nerve Growth Factor-β Antibody

serum, Chemicon®

Sinónimos:

NGFbeta

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250 μL
535,00 €

535,00 €


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250 μL
535,00 €

About This Item

Código UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

535,00 €


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origen biológico

rabbit

Nivel de calidad

forma del anticuerpo

serum

tipo de anticuerpo

primary antibodies

clon

polyclonal

reactividad de especies

mouse, rat, chicken, human

no debe reaccionar con

bovine

fabricante / nombre comercial

Chemicon®

técnicas

ELISA: suitable
immunohistochemistry: suitable
western blot: suitable

Nº de acceso NCBI

Nº de acceso UniProt

Condiciones de envío

wet ice

modificación del objetivo postraduccional

unmodified

Información sobre el gen

human ... NGF(4803)

Especificidad

Nerve growth factor-beta (NGF). Less than 1% cross-reactivity against recombinant human NT3, NT4 and BDNF by ELISA.

Inmunógeno

Mouse nerve growth factor-beta purified from salivary glands.

Aplicación

Immunohistochemistry at 1:500-1:5,000 (see suggested protocol).

Immunoblotting at 1:500-1:5,000.

ELISA at 1:500-1:5,000.

Inhibition of biological activity in vitro at 1:10-1:50.
BIOLOGICAL ACTIVITY: This antibody will completely inhibit the survival and neurite outgrowth actions of mouse NGF in chicken dorsal root ganglion neurons in vitro.

Use neat for in vivo animal studies.

Optimal working dilutions must be determined by end user.
Research Category
Neuroscience
Research Sub Category
Neurochemistry & Neurotrophins
This Anti-Nerve Growth Factor-β Antibody is validated for use in ELISA, WB, IH, FUNC for the detection of Nerve Growth Factor-β.

Ligadura / enlace

Replaces: 04-1119

Forma física

Whole rabbit antisera. Lyophilized. Reconstitute with 250 μL of sterile distilled water.

Almacenamiento y estabilidad

Maintain at -20°C to -70°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.

Información legal

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 1

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Tsia-Shu Lo et al.
The journal of obstetrics and gynaecology research, 43(1), 173-178 (2016-10-21)
By investigating the association of urodynamics and urogenital nerve growth factor (NGF) levels in vaginal mesh surgery, we may be able to associate the likelihood of postoperative lower urinary tract symptoms developing as a result of synthetic mesh implanted for
Sashwati Roy et al.
Nanomedicine : nanotechnology, biology, and medicine, 28, 102220-102220 (2020-05-19)
This work rests on our recent report on the successful use of tissue nanotransfection (TNT) delivery of Ascl1, Brn2, and Myt1l (TNTABM) to directly convert skin fibroblasts into electrophysiologically active induced neuronal cells (iN) in vivo. Here we report that
Daniel Aridgides et al.
PloS one, 8(2), e57450-e57450 (2013-02-26)
Cardiomyocytes express neurotrophin receptor TrkA that promotes survival following nerve growth factor (NGF) ligation. Whether TrkA also resides in cardiac fibroblasts (CFs) and underlies cardioprotection is unknown. To test whether CFs express TrkA that conveys paracrine signals to neighbor cardiomyocytes
A Vega et al.
Developmental neurobiology, 76(8), 832-846 (2015-11-13)
Neurons are able to segregate transmitters to different axon endings. Segregation is a plastic neuronal feature; it can be modulated by synaptic environment. We have demonstrated that neurotrophin and other cellular factors regulate segregation in sympathetic neurons in culture. Herein
F Jardí et al.
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society, 24(12), e580-e590 (2012-10-18)
Nerve growth factor (NGF)-mucosal mast cell (MMC) interaction has been implicated in the remodeling of enteric circuitries and associated functional changes. We investigated the involvement of NGF and its receptor TrkA in the altered colonic contractile activity observed in the

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