This gene is a member of the iron/manganese superoxide dismutase family. It encodes a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. This protein binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in this gene have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Inmunógeno
Epitope: AA G93 – Y217
Recombinant human SOD2
Aplicación
This Anti-SOD2 Antibody is validated for use in WB for the detection of SOD2.
Calidad
Routinely evaluated by immunoblot.
Descripción de destino
28 kDa
Información legal
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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