8.52005

Fmoc-Asp(OtBu)-OH

Novabiochem^®

• Sinónimos: Fmoc-Asp(OtBu)-OH, N-α-Fmoc-L-aspartic acid β-t.-butyl ester
• Fórmula empírica (notación de Hill): C₂₃H₂₅NO₆
• Número de CAS: 71989-14-5
• Peso molecular: 411.45
• Número MDL: MFCD00037131
• Código UNSPSC: 12352209
• Número índice de la CE: 276-251-7
• NACRES: NA.22

Propiedades

• Nivel de calidad: 400
• Línea del producto: Novabiochem^®
• Análisis: ≥98% (TLC); ≥98.0% (acidimetric); ≥99.0% (HPLC)
• formulario: powder
• idoneidad de la reacción: reaction type: Fmoc solid-phase peptide synthesis
• fabricante / nombre comercial: Novabiochem^®
• mp: 143-150 °C
• aplicaciones: peptide synthesis
• grupo funcional: carboxylic acid
• temp. de almacenamiento: 2-30°C
• InChI: 1S/C23H25NO6/c1-23(2,3)30-20(25)12-19(21(26)27)24-22(28)29-13-18-16-10-6-4-8-14(16)15-9-5-7-11-17(15)18/h4-11,18-19H,12-13H2,1-3H3,(H,24,28)(H,26,27)/p-1/t19-/m0/s1
• Clave InChI: FODJWPHPWBKDON-IBGZPJMESA-M

Descripción

Descripción general

High purity Fmoc-protected amino acid for research and process production of peptides, with very low levels of dipeptide, free-amino acids and acetic acid impurities.
Standard building block for introduction of aspartic acid amino-acid residues by Fmoc SPPS

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS

Aplicación

• Silybin liver research: Silybin A and B, as part of the silymarin complex, are extensively studied for their hepatoprotective properties. They play a crucial role in liver health by mitigating oxidative stress and enhancing regenerative processes in hepatic tissue (Cai et al., 2024).


• Silybin pharmacological research: The pharmacological effects of silybin, particularly its roles in inhibiting inflammation and modulating drug metabolizing enzymes, make it a valuable compound in therapeutic research, particularly for its benefits in hepatology and oncology (Hammad et al., 2024).

Ligadura / enlace

Replaces: 04-12-1013

Nota de análisis

Colour (visual): white to off white
Appearance of substance (visual): powder
Colour index (0,5 M in DMF): ≤ 150 Hazen
Identity (IR): passes test
Enantiomeric purity: ≥ 99.8 % (a/a)
Purity (HPLC): ≥ 99.0 % (a/a)
Fmoc-ß-Ala-OH (HPLC): ≤ 0.1 % (a/a)
Fmoc-ß-Ala-Asp (OtBu)-OH (HPLC): ≤ 0.1 % (a/a)
Fmoc-Asp(OtBu)-Asp(OtBu)-OH (HPLC): ≤ 0.1 % (a/a)
Fmoc-Asp-OH (HPLC): ≤ 0.1 % (a/a)
Assay free amino acid (GC): ≤ 0.2 %
Purity (TLC(011A)): ≥ 98 %
Purity (TLC(0811)): ≥ 98 %
Solubility (25 mmole in 50 ml DMF): clearly soluble
Assay (acidimetric): ≥ 98.0 %
Water (K. F.): ≤ 2.0 %
Ethyl acetate (HS-GC): ≤ 0.5 %
Acetate (IC): ≤ 0.02 %

To see the solvent systems used for TLC of Novabiochem^® products please click here.

Información legal

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable