8.08610

2,2,2-Trichloroethanol

for synthesis

• Sinónimos: 2,2,2-Trichloroethanol, ß,ß,ß-Trichloroethyl alcohol
• Fórmula empírica (notación de Hill): C₂H₃Cl₃O
• Número de CAS: 115-20-8
• Peso molecular: 149.40
• Número MDL: MFCD00004677
• Código UNSPSC: 12352104
• Número índice de la CE: 204-071-0
• NACRES: NA.22

Propiedades

• presión de vapor: 1.3 hPa ( 20 °C)
• Nivel de calidad: 200
• Análisis: ≥97.0% (GC)
• formulario: liquid
• temp. de autoignición: 151 °C
• potencia: 600 mg/kg LD₅₀, oral (Rat)
• pH: 5-6 (20 °C in H₂O, saturated solution)
• bp: 151-153 °C/1013 hPa
• mp: 17-18 °C
• temperatura de transición: flash point >110 °C
• densidad: 1.56 g/cm³ at 20 °C
• temp. de almacenamiento: 2-30°C
• InChI: 1S/C2H3Cl3O/c3-2(4,5)1-6/h6H,1H2
• Clave InChI: KPWDGTGXUYRARH-UHFFFAOYSA-N

Descripción

Aplicación

• Assessment of EDDP Perchlorate Stability in Biological Samples: An investigation focused on the stability of methaDoneand its main metabolite, EDDP perchlorate, in oral fluids. The study highlighted the importance of understanding metabolite stability for accurate drug testing and monitoring in forensic and clinical settings (Fucci and De Giovanni, 2008).



• EDDP Perchlorate in Drug Testing: EDDP perchlorate was examined in a forensic context using the SPME technique to simultaneously detect multiple drugs of abuse in saliva. This method underscores the utility of EDDP perchlorate as a reliable biomarker in toxicology studies and drug monitoring (Fucci, De Giovanni, and Chiarotti, 2003).



• Pharmacological Action of MethaDoneand Metabolites: Research explored the interaction of methaDoneand its metabolites, including EDDP perchlorate, with rat alpha3beta4 nicotinic receptors. These findings contribute to the understanding of the pharmacodynamic properties of methadone′s metabolites, relevant in the development of therapeutic and diagnostic strategies (Xiao et al., 2001).

Nota de análisis

Assay (GC, area%): ≥ 97.0 % (a/a)
Density (d 20 °C/ 4 °C): 1.551 - 1.561
Identity (IR): passes test
Due to its specific melting range the product may be solid, liquid, a solidified melt or a supercooled melt.

Información de seguridad

• Pictogramas: GHS05,GHS07
• Palabra de señalización: Danger
• Frases de peligro: H302 - H318 - H336
• Consejos de prudencia: P261 - P264 - P270 - P280 - P301 + P312 - P305 + P351 + P338
• Clasificaciones de peligro: Acute Tox. 4 Oral - Eye Dam. 1 - STOT SE 3
• Órganos de actuación: Central nervous system
• Código de clase de almacenamiento: 10 - Combustible liquids
• Clase de riesgo para el agua (WGK): WGK 1
• Punto de inflamabilidad (°F): 230.0 °F - closed cup
• Punto de inflamabilidad (°C): 110 °C - closed cup