538927

15d-PGJ₂

A metabolite of PGD₂that has recently been identified as a natural ligand for PPARγ-dependent adipogenesis in transfected NIH/3T3 cells and for PPARγ response element (PPRE) in CV-1 cells.

• Sinónimos: 15d-PGJ₂, Prostaglandin J₂, 15-Deoxy-Δ ^12,14, PPAR Agonist VII, PPARγ Agonist VI
• Fórmula empírica (notación de Hill): C₂₀H₂₈O₃
• Número de CAS: 87893-55-8
• Peso molecular: 316.43
• Número MDL: MFCD00065806
• Código UNSPSC: 12352211
• NACRES: NA.77

Propiedades

• Nivel de calidad: 100
• Análisis: ≥95% (HPLC)
• formulario: oil
• fabricante / nombre comercial: Calbiochem^®
• condiciones de almacenamiento: OK to freeze
• solubilidad: DMSO: 25 mg/mL; ethanol: 25 mg/mL
• Condiciones de envío: wet ice
• temp. de almacenamiento: −20°C
• InChI: 1S/C20H28O3/c1-2-3-4-5-6-10-13-18-17(15-16-19(18)21)12-9-7-8-11-14-20(22)23/h6-7,9-10,13,15-17H,2-5,8,11-12,14H2,1H3,(H,22,23)/b9-7-,10-6+,18-13+/t17-/m0/s1
• Clave InChI: VHRUMKCAEVRUBK-GODQJPCRSA-N

Descripción

Descripción general

A metabolite of PGD₂ that has recently been identified as a natural ligand for PPARγ-dependent adipogenesis in transfected 3T3 cells and for PPARγ response element (PPRE) in CV-1 cells. Competes with thiazolidinediones for PPARγ binding.

Acciones bioquímicas o fisiológicas

Cell permeable: no

Primary Target
A natural ligand for PPARγ-dependent adipogenesis

Product does not compete with ATP.

Reversible: no

Envase

Packaged under inert gas

Advertencia

Toxicity: Harmful (C)

Reconstitución

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Otras notas

Petrova, T.V., et al. 1999. Proc. Natl. Acad. Sci. USA96, 4668.
Ricote, M., et al. 1998. Nature 391, 79.
Forman, B.M., et al. 1995. Cell 83, 803.
Kliewer, S.A., et al. 1995. Cell83, 813.

Información legal

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable