211275

Capsaicin

An active constituent of cayenne pepper with excitatory and desensitizing effects on a subset of primary afferent sensory neurons.

• Sinónimos: Capsaicin, [(E)-N-(4-Hydroxy-3-methoxyphenyl)methyl]-8-methyl-6-nonenamide
• Fórmula empírica (notación de Hill): C₁₈H₂₇NO₃
• Número de CAS: 404-86-4
• Peso molecular: 305.41
• Número MDL: MFCD00017259
• Código UNSPSC: 12352200
• NACRES: NA.77

Propiedades

• Nivel de calidad: 100
• Análisis: ≥98% (TLC)
• formulario: solid
• fabricante / nombre comercial: Calbiochem^®
• condiciones de almacenamiento: OK to freeze
• color: off-white
• solubilidad: ethanol: 5 mg/mL
• Condiciones de envío: ambient
• temp. de almacenamiento: 10-30°C
• InChI: 1S/C18H27NO3/c1-14(2)8-6-4-5-7-9-18(21)19-13-15-10-11-16(20)17(12-15)22-3/h6,8,10-12,14,20H,4-5,7,9,13H2,1-3H3,(H,19,21)/b8-6+
• Clave InChI: YKPUWZUDDOIDPM-SOFGYWHQSA-N

Descripción

Descripción general

An active constituent of cayenne pepper with excitatory and desensitizing effects on a subset of primary afferent sensory neurons. An antagonist of acetylcholine-induced responses in rat PC12 cells. Exhibits anti-nociceptive and anti-inflammatory effects. Inhibits NF-κB activation by TNF. Reversibly inhibits platelet aggregation.

An active constituent of cayenne pepper. Has excitatory and desensitizing effects on a subset of primary afferent sensory neurons. An antagonist of acetylcholine-induced respones in rat pheochromocytoma cells. Exhibits antinociceptive and anti-inflammatory effects. Inhibits NF-κB activation by TNF. Reversibly inhibits platelet aggregation.

Advertencia

Toxicity: Toxic (F)

Reconstitución

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 2 months at -20°C.

Otras notas

Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.

Singh, S., et al. 1996. J. Immunol.157, 4412.
Nakazawa, K., et al. 1994. Br. J. Pharmacol.113, 296.
Simmons, D.D., et al. 1994. Int. J. Dev. Neurosci.12, 517.
Takaki, M., et al. 1994. J. Mol. Cell. Cardiol.26, 1227.
Bevan, S., and Szolcsanyi, J. 1990. Trends Pharmacol. Sci.11, 330.
Pernow, B., et al. 1985. J. Immunol.135, 8125.

Información legal

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Información de seguridad

• Pictogramas: GHS06,GHS08,GHS05
• Palabra de señalización: Danger
• Frases de peligro: H300,H315,H317,H318,H334,H335
• Consejos de prudencia: P261 - P264 - P280 - P301 + P310 - P302 + P352 - P305 + P351 + P338
• Clasificaciones de peligro: Acute Tox. 2 Oral - Eye Dam. 1 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
• Órganos de actuación: Respiratory system
• Código de clase de almacenamiento: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): 235.4 °F - closed cup
• Punto de inflamabilidad (°C): 113 °C - closed cup