06-1365

Anti-SRp40 Antibody

from rabbit

• Sinónimos: serine/arginine-rich splicing factor 5, Pre-mRNA-splicing factor SRP40, Delayed-early protein HRS, SR splicing factor 5, splicing factor, arginine/serine-rich 5
• Código UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Propiedades

• origen biológico: rabbit
• Nivel de calidad: 100
• forma del anticuerpo: purified antibody
• tipo de anticuerpo: primary antibodies
• clon: polyclonal
• reactividad de especies: human, mouse
• técnicas: immunoprecipitation (IP): suitable; western blot: suitable
• Nº de acceso NCBI: NP_001034554
• Nº de acceso UniProt: Q13243
• Condiciones de envío: wet ice
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: human ... SRSF5(6430)

Descripción

Descripción general

SRp40 is a nuclear phosphoprotein that is a member of the SR family of proteins. Essential for alternative splicing regulation this protein is also known as Serine/arginine-rich splicing factor 5, and Delayed-early protein HRS. The SRp40 protein is a component of the spliceosome complex and appears to play a role in splice site selection. Over-expression of SRp40 is thought to cause increased chondrogenic differentiation of mesenchymal cells. In addition, increased expression of SRp40 has been found in breast tumor tissues and is associated with alternative pre-mRNA splicing of CD44.

Inmunógeno

Linear peptide corresponding to human SRp40.

Aplicación

Immunoprecipitation Analysis:
A representative lot was used by an independent laboratory in IP. (Jiang, K., et al. (2009). Endocrinology. 150(5):2087-2097.)

Research Category
Epigenetics & Nuclear Function

Research Sub Category
RNA Metabolism & Binding Proteins

Use Anti-SRp40 Antibody (Rabbit Polyclonal Antibody) validated in WB, IP to detect SRp40 also known as serine/arginine-rich splicing factor 5, Pre-mRNA-splicing factor SRP40.

Calidad

Evaluated by Western Blot in HeLa cell lysate.

Western Blot Analysis: 1:500 dilution of this antibody detected SRp40 on 10 µg of HeLa cell lysate.

Descripción de destino

~38 kDa observed

Forma física

Format: Purified

Protein A

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Almacenamiento y estabilidad

Stable for 1 year at 2-8°C from date of receipt.

Nota de análisis

Control
HeLa cell lysate

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 12 - Non Combustible Liquids
• Clase de riesgo para el agua (WGK): WGK 1
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable