T-072

Tadalafil solution

1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant^®

• Fórmula empírica (notación de Hill): C₂₂H₁₉N₃O₄
• Número de CAS: 171596-29-5
• Peso molecular: 389.40
• Número CE: 200-835-2
• Número MDL: MFCD07771966
• Código UNSPSC: 41116107
• ID de la sustancia en PubChem: 329826616
• NACRES: NA.24

Propiedades

• grado: certified reference material
• formulario: liquid
• Características: Snap-N-Spike^®/Snap-N-Shoot^®
• envase: ampule of 1 mL
• fabricante / nombre comercial: Cerilliant^®
• concentración: 1.0 mg/mL in acetonitrile
• técnicas: gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• aplicaciones: pharmaceutical (small molecule)
• formato: single component solution
• temp. de almacenamiento: −20°C
• cadena SMILES: O=C1N(C)CC(N2[C@H](C3=CC(OCO4)=C4C=C3)C5=C(C(C=CC=C6)=C6N5)C[C@@]21[H])=O
• InChI: 1S/C22H19N3O4/c1-24-10-19(26)25-16(22(24)27)9-14-13-4-2-3-5-15(13)23-20(14)21(25)12-6-7-17-18(8-12)29-11-28-17/h2-8,16,21,23H,9-11H2,1H3/t16-,21-/m1/s1
• Clave InChI: WOXKDUGGOYFFRN-IIBYNOLFSA-N
• Información sobre el gen: human ... PDE5A(8654)

Descripción

Descripción general

Tadalafil is an erectile-dysfunction drug marketed under the trade name Cialis^®. This Certified Spiking Solution^® is suitable for use in numerous testing applications such as clinical toxicology, forensic analysis, urine drug testing, or calibrator preparation.

Aplicación

• Universal Quantitation of PDE5 Inhibitors: A study highlights the use of high-performance liquid chromatography with charged aerosol detection to universally quantitate undeclared phosphodiesterase-5 inhibitors, including tadalafil, in herbal dietary supplements. This method ensures the integrity of dietary supplements and protects consumers from potential health risks (Poplawska et al., 2013).


• Drug Screening with 3D-Printed Electrochemical Cells: Research developed a multi-sensor compatible 3D-printed electrochemical cell for voltammetric drug screening, applicable to tadalafil and other drugs. This innovative approach enhances drug analysis efficiency and accuracy, facilitating rapid screening in pharmaceutical research (Ferreira et al., 2021).


• Solid Dispersions for Enhanced Solubility: A study on the physical stability of solid dispersions of tadalafil in PVP-VA investigates the thermodynamic solubility of the drug, critical for improving bioavailability in pharmaceutical formulations. This research contributes to the development of more effective and reliable drug delivery systems (Wlodarski et al., 2015).

Información legal

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation

Cialis is a registered trademark of Eli Lilly and Co.

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Información de seguridad

• Pictogramas: GHS02,GHS07
• Palabra de señalización: Danger
• Frases de peligro: H225,H302 + H312 + H332,H319
• Consejos de prudencia: P210 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P312 - P305 + P351 + P338
• Clasificaciones de peligro: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2
• Código de clase de almacenamiento: 3 - Flammable liquids
• Clase de riesgo para el agua (WGK): WGK 2
• Punto de inflamabilidad (°F): 35.6 °F - closed cup
• Punto de inflamabilidad (°C): 2 °C - closed cup