M-105
Methyl-D3-malonic acid solution
1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®
Iniciar sesiónpara Ver la Fijación de precios por contrato y de la organización
About This Item
Fórmula empírica (notación de Hill):
C4H3O4D3
Número de CAS:
Peso molecular:
121.11
Número CE:
Código UNSPSC:
41116107
NACRES:
NA.24
Productos recomendados
grado
certified reference material
formulario
liquid
Características
Snap-N-Spike®/Snap-N-Shoot®
envase
ampule of 1 mL
fabricante / nombre comercial
Cerilliant®
concentración
1.0 mg/mL in acetonitrile
técnicas
gas chromatography (GC): suitable
liquid chromatography (LC): suitable
aplicaciones
clinical testing
pharmaceutical (small molecule)
formato
single component solution
temp. de almacenamiento
−20°C
cadena SMILES
[2H]C([2H])([2H])C(C(O)=O)C(O)=O
InChI
1S/C4H6O4/c1-2(3(5)6)4(7)8/h2H,1H3,(H,5,6)(H,7,8)/i1D3
Clave InChI
ZIYVHBGGAOATLY-FIBGUPNXSA-N
Descripción general
Methylmalonic acid, a malonic acid derivative, is a vital intermediate in the metabolism of fat and proteins and plays a key role in energy metabolism. Elevated methylmalonic acid levels can be caused by an inborn error of metabolism leading to methylmalonic aciduria or indicate early vitamin B<sub>12</sub> deficiency. This internal standard is suitable for quantitation of methylmalonic acid levels by LC/MS or GC/MS in newborn screening and clinical testing applications to test for methylmalonic acidemia and diagnose vitamin B<sub>12</sub> deficiency.
Aplicación
- Assessment of Vitamin B-12 Status: Methyl-D3-malonic acid, as a deuterated derivative of malonic acid, was highlighted for its application in quantifying vitamin B-12 status using dried blood spots. This method provides a stable, precise measure and is useful in nutritional research and clinical diagnostics (Schroder et al., 2014).
- Improvement of Analytical Methods: Methyl-D3-malonic acid was used in a gas chromatography-mass spectrometry (GC-MS) technique to quantify methylmalonic acid in serum. This application underlines its role in improving diagnostic assays by offering enhanced precision and reliability in biochemical measurements (Straczek et al., 1993).
Información legal
CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
Producto relacionado
Referencia del producto
Descripción
Precios
Palabra de señalización
Danger
Frases de peligro
Clasificaciones de peligro
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2
Código de clase de almacenamiento
3 - Flammable liquids
Clase de riesgo para el agua (WGK)
WGK 2
Punto de inflamabilidad (°F)
35.6 °F - closed cup
Punto de inflamabilidad (°C)
2 °C - closed cup
Certificados de análisis (COA)
Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»
¿Ya tiene este producto?
Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.
Los clientes también vieron
Patrick J O'Hern et al.
eLife, 6 (2017-05-04)
Spinal Muscular Atrophy (SMA) is caused by diminished Survival of Motor Neuron (SMN) protein, leading to neuromuscular junction (NMJ) dysfunction and spinal motor neuron (MN) loss. Here, we report that reduced SMN function impacts the action of a pertinent microRNA
Laura Nadal et al.
Frontiers in aging neuroscience, 9, 24-24 (2017-02-24)
The development of the nervous system involves the overproduction of synapses but connectivity is refined by Hebbian activity-dependent axonal competition. The newborn skeletal muscle fibers are polyinnervated but, at the end of the competition process, some days later, become innervated
Alessandra Lo Cicero et al.
Scientific reports, 6, 34798-34798 (2016-10-16)
Hutchinson-Gilford progeria syndrome (HGPS) is a rare fatal genetic disorder that causes systemic accelerated aging in children. Thanks to the pluripotency and self-renewal properties of induced pluripotent stem cells (iPSC), HGPS iPSC-based modeling opens up the possibility of access to
Laura Nadal et al.
Molecular brain, 9(1), 67-67 (2016-06-25)
The development of the nervous system involves an initially exuberant production of neurons that make an excessive number of synaptic contacts. The initial overproduction of synapses promotes connectivity. Hebbian competition between axons with different activities (the least active are punished)
Maria Bertuzzi et al.
Scientific reports, 8(1), 1988-1988 (2018-02-02)
While cholinergic neuromodulation is important for locomotor circuit operation, the specific neuronal mechanisms that acetylcholine employs to regulate and fine-tune the speed of locomotion are largely unknown. Here, we show that cholinergic interneurons are present in the zebrafish spinal cord
Nuestro equipo de científicos tiene experiencia en todas las áreas de investigación: Ciencias de la vida, Ciencia de los materiales, Síntesis química, Cromatografía, Analítica y muchas otras.
Póngase en contacto con el Servicio técnico