L-029

Lacosamide solution

1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant^®

• Fórmula empírica (notación de Hill): C₁₃H₁₈N₂O₃
• Número de CAS: 175481-36-4
• Peso molecular: 250.29
• Número MDL: MFCD08272557
• Código UNSPSC: 41116107
• ID de la sustancia en PubChem: 329817347
• NACRES: NA.24

Propiedades

• grado: certified reference material
• formulario: liquid
• Características: Snap-N-Spike^®/Snap-N-Shoot^®
• envase: ampule of 1 mL
• fabricante / nombre comercial: Cerilliant^®
• concentración: 1.0 mg/mL in acetonitrile
• técnicas: gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• aplicaciones: clinical testing
• formato: single component solution
• temp. de almacenamiento: −20°C
• cadena SMILES: CC(N[C@H](COC)C(NCC1=CC=CC=C1)=O)=O
• InChI: 1S/C13H18N2O3/c1-10(16)15-12(9-18-2)13(17)14-8-11-6-4-3-5-7-11/h3-7,12H,8-9H2,1-2H3,(H,14,17)(H,15,16)/t12-/m1/s1
• Clave InChI: VPPJLAIAVCUEMN-GFCCVEGCSA-N
• Información sobre el gen: human ... SCN10A(6336) , SCN11A(11280) , SCN1A(6323) , SCN2A(6326) , SCN3A(6328) , SCN4A(6329) , SCN5A(6331) , SCN7A(6332) , SCN8A(6334) , SCN9A(6335)

Descripción

Descripción general

A Certified Spiking Solution^® suitable for use in LC/MS or GC/MS applications in clinical toxicology, forensic analysis, urine drug testing, prescription monitoring or pharmaceutical research. Lacosamide is a new antiepileptic drug developed for the adjunctive treatment of partial-onset seizures and diabetic neuropathic pain. The drug is marketed under the trade name Vimpat^®.

Aplicación

• Lacosamide solution as a mass spectrometry standard: A recent development in analytical techniques features a UPLC-MS/MS method for determining lacosamide and its metabolites, essential for drug-drug interaction studies. This research underlines lacosamide′s role as a critical pharmaceutical research tool in the study of anti-epileptic drugs and their interactions (Chen et al., 2023).


• Lacosamide as an anticonvulsant in pharmacological research: Investigations on the effects of chronic lacosamide on ovarian tissue in rats highlight the broader physiological impacts of long-term anti-seizure medication use. Such studies are critical for assessing the reproductive safety of anticonvulsants, informing guidelines for their use in women of childbearing age (Kart et al., 2022).

Información legal

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Vimpat is a registered trademark of Harris FRC Corporation

Información de seguridad

• Pictogramas: GHS02,GHS07
• Palabra de señalización: Danger
• Frases de peligro: H225,H302 + H312 + H332,H319
• Consejos de prudencia: P210 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P312 - P305 + P351 + P338
• Clasificaciones de peligro: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2
• Código de clase de almacenamiento: 3 - Flammable liquids
• Clase de riesgo para el agua (WGK): WGK 2
• Punto de inflamabilidad (°F): 35.6 °F - closed cup
• Punto de inflamabilidad (°C): 2 °C - closed cup