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850520P

Avanti

n-dodecyl-β-D-maltoside (DDM)

Avanti Research™ - A Croda Brand

Sinónimos:

DDM; lauryl maltoside; dodecyl 4-O-α-D-glucopyranosyl-β-D-glucopyranoside

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About This Item

Fórmula empírica (notación de Hill):
C24H46O11
Número de CAS:
69227-93-6
Peso molecular:
510.62
Código UNSPSC:
12161902
NACRES:
NA.25

descripción

n-dodecyl-β-D-maltopyranoside

Análisis

>99% (contains <2% alpha isomer, TLC)

formulario

powder

mol peso

510.62 g/mol

envase

pkg of 1 × 1 g (850520P-1g)
pkg of 1 × 25 g (850520P-25g)
pkg of 1 × 5 g (850520P-5g)

fabricante / nombre comercial

Avanti Research™ - A Croda Brand

Condiciones de envío

dry ice

temp. de almacenamiento

−20°C

cadena SMILES

OC[C@H]1O[C@@H](OCCCCCCCCCCCC)[C@H](O)[C@@H](O)[C@@H]1O[C@@H]2[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O2

InChI

1S/C24H46O11/c1-2-3-4-5-6-7-8-9-10-11-12-32-23-21(31)19(29)22(16(14-26)34-23)35-24-20(30)18(28)17(27)15(13-25)33-24/h15-31H,2-14H2,1H3/t15-,16-,17-,18+,19-,20-,21-,22-,23-,24-/m1/s1

Clave InChI

NLEBIOOXCVAHBD-QKMCSOCLSA-N

Categorías relacionadas

Descripción general

n-dodecyl-β-D-maltoside (DDM) is a sugar-based surfactant.
DDM is the most widely used detergent for the isolation and purification of GPCR′s. In addition, LacY likely favors a higher-energy intermediate periplasmic-open conformation in situ, but collapses to a lower-energy periplasmic-closed conformation in DDM after purification. It is interesting to note that the branched-chain maltoside detergents stabilize LacY in the membrane-embedded form.

Aplicación

n-dodecyl-β-D-maltoside (DDM) has been used to solubilize mitochondrial extracts of fibroblasts to perform one-dimensional blue-native PAGE (BN-PAGE) analysis for assembled oxidative phosphorylation (OXPHOS) complexes.

Acciones bioquímicas o fisiológicas

n-dodecyl-β-D-maltoside (DDM) exhibits biocompatibility and biodegradability. It serves as a facilitator of electron transfer in order to decrease the oxidation potential of 3,4-ethylenedioxythiophene (EDOT). It can also increase the solubility of EDOT in aqueous solution.

Envase

125 mL Amber Wide Mouth Glass Bottle with Screw Cap (850520P-25g)
20 mL Clear Glass Screw Cap Vial (850520P-1g)
30 mL Amber Wide Mouth Screw Cap Glass Bottle (850520P-5g)

Información legal

Avanti Research is a trademark of Avanti Polar Lipids, LLC

también adquirido normalmente con este producto

Referencia del producto
Descripción
Precios

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Biallelic mutations in ATP5F1D, which encodes a subunit of ATP synthase, cause a metabolic disorder
Olahova M, et al.
American Journal of Human Genetics, 102(3), 494-504 (2018)
Truc Do et al.
Nature microbiology, 5(2), 291-303 (2020-01-15)
Bacteria are protected by a polymer of peptidoglycan that serves as an exoskeleton1. In Staphylococcus aureus, the peptidoglycan assembly enzymes relocate during the cell cycle from the periphery, where they are active during growth, to the division site where they
Electrochemical polymerization of 3, 4-ethylenedioxythiophene in aqueous solution containing N-dodecyl-beta-d-maltoside
Zhang S, et al.
European Polymer Journal, 42(1), 149-160 (2006)
Anastasiia Gusach et al.
Nature communications, 10(1), 5573-5573 (2019-12-08)
Cysteinyl leukotriene G protein-coupled receptors CysLT1 and CysLT2 regulate pro-inflammatory responses associated with allergic disorders. While selective inhibition of CysLT1R has been used for treating asthma and associated diseases for over two decades, CysLT2R has recently started to emerge as
Xiaoxu Jiang et al.
Proceedings of the National Academy of Sciences of the United States of America, 109(12), E698-E704 (2012-02-23)
LacY mutant Cys154 → Gly exhibits a periplasmic-closed crystal structure identical to the WT, but is periplasmic-open in the membrane. The mutant hardly catalyzes transport, but binds galactosides from either side of the membrane with the same affinity and is
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