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Merck

840635P

Avanti

12:0 PA

1,2-dilauroyl-sn-glycero-3-phosphate (sodium salt), powder

Sinónimos:

1,2-didodecanoyl-sn-glycero-3-phosphate (sodium salt); DLPA; PA(12:0/12:0)

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25 MG
112,00 €
200 MG
336,00 €

112,00 €


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25 MG
112,00 €
200 MG
336,00 €

About This Item

Fórmula empírica (notación de Hill):
C27H52O8PNa
Número de CAS:
Peso molecular:
558.66
Número MDL:
Código UNSPSC:
51191904
NACRES:
NA.25

112,00 €


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Ensayo

>99% (TLC)

Formulario

powder

envase

pkg of 1 × 200 mg (840635P-200mg)
pkg of 1 × 25 mg (840635P-25mg)

fabricante / nombre comercial

Avanti Research - A Croda Brand 840635P

tipo de lípido

phospholipids
cardiolipins

Condiciones de envío

dry ice

temp. de almacenamiento

−20°C

cadena SMILES

[H][C@@](COP([O-])(O)=O)(OC(CCCCCCCCCCC)=O)COC(CCCCCCCCCCC)=O.[Na+]

InChI

1S/C27H53O8P.Na/c1-3-5-7-9-11-13-15-17-19-21-26(28)33-23-25(24-34-36(30,31)32)35-27(29)22-20-18-16-14-12-10-8-6-4-2;/h25H,3-24H2,1-2H3,(H2,30,31,32);/q;+1/p-1/t25-;/m1./s1

Clave InChI

CIOHBYXGWWPOIS-VQIWEWKSSA-M

Descripción general

12:0 PA (1,2-dilauroyl-sn-glycero-3-phosphate) is a sodium salt of modified lipid, wherein C-1, C-2 of glycerol is substituted with didodecanoyl and C-3 of glycerol is substituted with phosphatidic acid group.

Aplicación

12:0 PA (1,2-dilauroyl-sn-glycero-3-phosphate (sodium salt)) has been used as an internal lipid standard in the matrix-assisted laser desorption/ionization Fourier transform ion cyclotron resonance mass spectrometry (MALDI FT-ICR MS) analysis.[1] It may be used as a lipid standard:
  • for the quantification of phospholipids by high-performance liquid chromatography coupled to tandem mass spectrometryelectrospray ionization tandem mass spectrometry (HPLC/ESI-MS/MS)[2]
  • for the quantification of lipids in cold-pressed rapeseed oils based on direct infusion electrospray ionization tandem mass spectrometry[3]
  • in liquid chromatography tandem mass spectrometry (LC-MS/MS) analysis[4]

Acciones bioquímicas o fisiológicas

Phosphatidic acid (PA) might serve as a modulator of phagocyte respiratory burst.[5]

Envase

5 mL Amber Glass Screw Cap Vial (840635P-200mg)
5 mL Amber Glass Screw Cap Vial (840635P-25mg)

Información legal

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable


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Certificados de análisis (COA)

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Glycerolipids in signal transduction
New comprehensive biochemistry, 31, 237-255 null
Marie Garnier-Lhomme et al.
PloS one, 4(1), e4255-e4255 (2009-01-24)
The cytoplasm of eukaryotic cells is a highly dynamic compartment where membranes readily undergo fission and fusion to reorganize the cytoplasmic architecture, and to import, export and transport various cargos within the cell. The double membrane of the nuclear envelope
Richard D Byrne et al.
Cellular signalling, 19(5), 913-922 (2006-12-23)
Nuclear envelope assembly is an essential event in each cell cycle but the proteins and lipids involved in its regulation remain mostly unknown. Assembly involves membrane fusions but neither specific SNAREs nor Rab GTPases have been identified in its control.
Ya Xie et al.
Food chemistry, 285, 194-203 (2019-02-25)
Microwave pretreatment of rapeseeds prior to cold-pressing is a simple and desirable method for producing high quality oils. In this study, a rapid and sensitive lipid profiling platform employing an accurate quantification strategy was established based on direct infusion electrospray
Yuchen Sun et al.
Metabolites, 9(11) (2019-11-07)
Extracellular vesicles (EVs) consist of lipid bilayers, occur in various biofluids, and are invaluable in biomarker screening. Liquid chromatography coupled with high-resolution mass spectrometry (LC-MS) was recently used to study comprehensive EV lipid profiles in vitro. The aim of this

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