840520P

16:0 Lysyl PG

Avanti Research^™ - A Croda Brand

• Sinónimos: Lysyl-DPPG
• Fórmula empírica (notación de Hill): C₄₄H₈₉Cl₂N₂O₁₁P
• Número de CAS: 1246303-06-9
• Peso molecular: 924.06
• Código UNSPSC: 51191904
• NACRES: NA.25

Propiedades

• descripción: 1,2-dipalmitoyl-sn-glycero-3-[phospho-rac-(3-lysyl(1-glycerol))] (chloride salt)
• Ensayo: >99% (up to 15% acyl migration on lysine, TLC)
• Formulario: powder
• envase: pkg of 1 × 1 mg (840520P-1mg); pkg of 1 × 5 mg (840520P-5mg)
• fabricante / nombre comercial: Avanti Research^™ - A Croda Brand
• tipo de lípido: bioactive lipids; phospholipids
• Condiciones de envío: dry ice
• temp. de almacenamiento: −20°C
• cadena SMILES: OC(COC([C@@](CCCC[NH3+])([H])[NH3+])=O)COP(O)(OC[C@]([H])(OC(CCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O)=O.[Cl-].[Cl-]
• InChI: 1S/C44H87N2O11P.2ClH/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-32-42(48)53-37-40(57-43(49)33-28-26-24-22-20-18-16-14-12-10-8-6-4-2)38-56-58(51,52)55-36-39(47)35-54-44(50)41(46)31-29-30-34-45;;/h39-41,47H,3-38,45-46H2,1-2H3,(H,51,52);2*1H/t39?,40-,41+;;/m1../s
• Clave InChI: CDKVLSICTGSTLD-WEQCYVBHSA-N

Descripción

Descripción general

Lysyl PG is one of the predominant lipid constituents of gram-positive bacteria and Enterococcus faecalis.

Aplicación

16:0 Lysyl PG is suitable for use:

• as a standard for lipidomics analysis by using three-dimensional hydrophilic interaction liquid chromatography-ion mobility-mass spectrometry (HILIC-IM-MS)[1]
• to analyse the influence of peptides on the phase transition behavior of lipids by fourier transform infrared spectroscopy[2]
• in the preparation of artificial vesicles modelled on the lipid composition of Staphylococcal membranes to study the effect of galloyl catechins[3]

Acciones bioquímicas o fisiológicas

Lysyl phosphatidylglycerol (Lysyl-PG) is formed by lysinylation of PG in the presence of multiprotein resistance factor (MprF). MprF flips lysyl-PG from inner to outer membrane leaflet, increasing the positive charge on the membrane.[1] Lysyl PG is essential for domain formation and antibiotic resistance.[4]

Envase

5 mL Amber Glass Screw Cap Vial (840520P-1mg)

5 mL Amber Glass Screw Cap Vial (840520P-5mg)

Información legal

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): No data available
• Punto de inflamabilidad (°C): No data available