840012C

Heart CA

Avanti Research^™ - A Croda Brand

• Sinónimos: Cardiolipin (Heart, Bovine) (sodium salt)
• Número de CAS: 383907-10-6
• Número MDL: MFCD11974098
• Código UNSPSC: 12352211
• NACRES: NA.25

Propiedades

• Ensayo: >99% (TLC)
• Formulario: liquid
• envase: pkg of 1 × 2 mL (840012C-50mg); pkg of 1 × 2.5 mL (840012C-25mg); pkg of 1 × 4 mL (840012C-100mg)
• fabricante / nombre comercial: Avanti Research^™ - A Croda Brand
• concentración: 10 mg/mL (840012C-25mg); 25 mg/mL (840012C-100mg); 25 mg/mL (840012C-50mg)
• tipo de lípido: phosphoglycerides
• Condiciones de envío: dry ice
• temp. de almacenamiento: −20°C
• cadena SMILES: [Na+].[Na+].[P](=O)([O-])(OC[C@H](OC(=O)CCCCCCC\C=C/C\C=C/CCCCC)COC(=O)CCCCCCC\C=C/C\C=C/CCCCC)OCC(O)CO[P](=O)([O-])OC[C@H](OC(=O)CCCCCCC\C=C/C\C=C/CCCCC)COC(=O)CCCCCCC\C=C/C\C=C/CCCCC
• InChI: 1S/C81H142O17P2.2Na/c1-5-9-13-17-21-25-29-33-37-41-45-49-53-57-61-65-78(83)91-71-76(97-80(85)67-63-59-55-51-47-43-39-35-31-27-23-19-15-11-7-3)73-95-99(87,88)93-69-75(82)70-94-100(89,90)96-74-77(98-81(86)68-64-60-56-52-48-44-40-36-32-28-24-20-16-12-8-4)72-92-79(84)66-62-58-54-50-46-42-38-34-30-26-22-18-14-10-6-2;;/h21-28,33-40,75-77,82H,5-20,29-32,41-74H2,1-4H3,(H,87,88)(H,89,90);;/q;2*+1/p-2/b25-21-,26-22-,27-23-,28-24-,37-33-,38-34-,39-35-,40-36-;;/t76-,77-;;/m1../s1
• Clave InChI: ZGSPNIOCEDOHGS-LBOJVHLDSA-L

Descripción

Descripción general

Cardiolipin is a phospholipid found in the inner membrane of the mitochondria. It is synthesized from phosphatidylglycerol and cytidinediphosphate-diacylglycerol.[1] It consists of two phosphatidyl residues, which are linked by a glycerol group.[2]

Aplicación

Heart CA has been used in the Mycobacterium lipid extraction and in β- Hexosaminidase release and calcium mobilization assays.[3] It maybe used for liposome synthesis[4]. It may also be used as a lipid standard for the in situ analysis and characterization of cardiolipins.[5]

Acciones bioquímicas o fisiológicas

Cardiolipin is involved in maintaining the structure and function of the mitochondria. It also serves as a co-factor for stimulating mitochondrial enzymes and mediates mitochondrial apoptosis. Cardiolipin is associated with the oxidative phosphorylation system for the adenine triphosphate (ATP) synthesis in the inner membrane of the mitochondria.[1] Deficiency of cardiolipin is associated with variation of mitochondrial membrane structure and function. It is also associated with Barth syndrome.[2][1]

Envase

5 mL Clear Glass Sealed Ampule (840012C-100mg)

5 mL Clear Glass Sealed Ampule (840012C-25mg)

5 mL Clear Glass Sealed Ampule (840012C-50mg)

Información legal

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Información de seguridad

• Pictogramas: GHS06,GHS08
• Palabra de señalización: Danger
• Frases de peligro: H302,H315,H319,H331,H336,H351,H361d,H372,H412
• Consejos de prudencia: P201 - P273 - P301 + P312 + P330 - P302 + P352 - P304 + P340 + P311 - P308 + P313
• Clasificaciones de peligro: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
• Órganos de actuación: Central nervous system, Liver,Kidney
• Código de clase de almacenamiento: 6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): does not flash
• Punto de inflamabilidad (°C): does not flash