GEN-7006

Cationic Liposomes for DNA/RNA delivery

DOTAP:DOPE (1:1) containing 0.5% Rhod-PE (Fluorescent)

• Código UNSPSC: 12352211
• NACRES: NA.25

Propiedades

• Nivel de calidad: 100
• contiene: Rhod-PE (1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-(lissamine; rhodamine B sulfonyl)) as fluorescent label
• composición: Deionized RNAse-free Water
• concentración: 0.02 mM (Rhod-PE); 2 mM (DOPE); 2 mM (DOTAP)
• impurezas: 1:1 mol/mol DOTAP:DOPE
• tamaño de partícula: 100 nm
• pH: 7
• cociente de absorbancia: _{560/583 nm}

Descripción

Descripción general

Cationic liposomes are traditionally used for the delivery of genetic materials such as various types of DNA (pDNA, cDNA, CpG DNA, oligonucleotide, antisense oligonucleotide), various types of RNA such as (siRNA, mRNA) and nucleic acid mimics (NAMs). The positive, cationic charge of the lipids is used to neutralize the negative charge of nucleic acids and results in greater encapsulation efficiency, cellular uptake and endosomal delivery.

Aplicación

Drug delivery
Gene delivery
Lipid-protein interactions

Almacenamiento y estabilidad

Liposomes should never be frozen. Liposomes should be stored in the dark at 4°C, except when brought to room temperature for brief periods prior to use.

Liposomes are made under sterile conditions. If you need to take multiple aliquots out of the vial, it is advised to take extreme care in not contaminating the vial. It is recommended to handle the vial under a sterile hood to maintain the sterility of the product. Liposomes should never be frozen. Ice crystals that form during freezing will rupture the lipid membrane of the liposomes and change the size of liposomes particles.

Información legal

Genesome is a trademark of Encapsula NanoSciences

Product of Encapsula Nanosciences

Cláusula de descargo de responsabilidad

For research use only

Información de seguridad

• Código de clase de almacenamiento: 12 - Non Combustible Liquids
• Clase de riesgo para el agua (WGK): WGK 1
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable